View in Gene3D

CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 635022: ABC transporter ATP-binding component

There are 9 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphate-transporting ATPase. [EC: 3.6.3.27]
ATP + H(2)O + phosphate(Out) = ADP + phosphate + phosphate(In).
  • A bacterial enzyme that imports phosphate anions.
 88 A0A023YSC3 A0A025C9N6 A0A029L2U9 A0A069XNN0 A0A070SUB6 A0A070UWA9 A0A074IN75 A0A075KNS1 A0A0A0FA27 A0A0D1I9W9
(78 more...)
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 21 A0A085AET5 A0A085GEB1 A0A085GSL4 A0A085HLS2 A0A085IJX7 A0A085JGA8 A0A091BYD6 A0A091CC46 A0A0E2BLM3 A0A0E2BS77
(11 more...)
Glycerol-3-phosphate-transporting ATPase. [EC: 3.6.3.20]
ATP + H(2)O + glycerol-3-phosphate(Out) = ADP + phosphate + glycerol-3- phosphate(In).
  • A bacterial enzyme that imports phosphorylated glycerol.
 16 A0A090DAU7 A0A090F2L7 A0A0H5DFY8 A0A0M6Y4R3 A0A0M6Z1B2 A0A0N7LYS3 A0A0P1E6Y6 A0A0P1ECU3 A0A0P1ESS7 A0A0P1FNS6
(6 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
 16 A0A085AET5 A0A085GEB1 A0A085GSL4 A0A085HLS2 A0A085IJX7 A0A085JGA8 A0A091BYD6 A0A091CC46 A0A198GN77 A0A198GPK5
(6 more...)
Sulfate-transporting ATPase. [EC: 3.6.3.25]
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
  • A bacterial enzyme that imports sulfate and thiosulfate anions.
 9 A0A0R1MN02 A0A0R2BUS3 A0A0R2FEN5 F3MP91 G2KTB7 K7VVI3 U6F8Q6 U6FE38 U6FSN3
Fe(3+)-transporting ATPase. [EC: 3.6.3.30]
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
  • A bacterial enzyme that imports ferric cations.
 6 A0A110LSE8 A0A1B8PA56 E1X7Z5 E7A4N0 F4FR58 Q57213
Polyamine-transporting ATPase. [EC: 3.6.3.31]
ATP + H(2)O + polyamine(Out) = ADP + phosphate + polyamine(In).
  • A bacterial enzyme that imports putrescine and spermidine.
 4 A0A1A7T5A4 A0A1L8WZK7 M7NFC4 R2RG43
Maltose-transporting ATPase. [EC: 3.6.3.19]
ATP + H(2)O + maltose(Out) = ADP + phosphate + maltose(In).
  • Comprises bacterial enzymes that import maltose and maltose oligosaccharides.
 3 A0A0M7A7Q6 A0A0M7A8W4 A0A0P1GWZ5
Xenobiotic-transporting ATPase. [EC: 3.6.3.44]
ATP + H(2)O + xenobiotic(In) = ADP + phosphate + xenobiotic(Out).
  • Enzymes of Gram-positive bacteria and eukaryotic cells that export a number of drugs, with unusual specificity, covering various groups of unrelated substances, while ignoring some that are closely related structurally.
  • Several distinct enzymes may be present in a single eukaryotic cell.
  • Many of them transport glutathione conjugates with drugs.
  • Some also show some 'flippase' (EC 3.6.3.1) activity.
  • Formerly EC 3.6.3.45.
 1 U5RZH8
CATH-Gene3D is a Global Biodata Core Resource Learn more...