The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 635012: ATP-dependent RNA helicase glh-1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
JUN kinase binding GO:0008432
Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.
4 O01836 (/IPI) O76743 (/IPI) P34689 (/IPI) Q966L9 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 O01836 (/IPI) P34689 (/IPI) Q966L9 (/IPI)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
3 O01836 (/IPI) P34689 (/IPI) Q966L9 (/IPI)
RNA helicase activity GO:0003724
Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix.
2 P34689 (/IDA) Q966L9 (/IDA)
ATP-dependent RNA helicase activity GO:0004004
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
2 O13622 (/ISS) Q8IEP2 (/ISS)
DEAD/H-box RNA helicase binding GO:0017151
Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase.
2 O01836 (/IPI) P34689 (/IPI)
RNA helicase activity GO:0003724
Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix.
1 O76743 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
2 P34689 (/IMP) Q966L9 (/IMP)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
2 P34689 (/IMP) Q966L9 (/IMP)
RNA metabolic process GO:0016070
The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
2 P34689 (/ISS) Q966L9 (/ISS)
Gamete generation GO:0007276
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
1 O76743 (/IMP)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
1 O13622 (/NAS)
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 O76743 (/IMP)
Mitochondrial mRNA processing GO:0090615
Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.
1 O13622 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
4 O01836 (/IDA) O76743 (/IDA) P34689 (/IDA) Q966L9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O76743 (/IDA) P34689 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O13622 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 O13622 (/ISS)
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