The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 634810: 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphat...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
6-phosphofructo-2-kinase. [EC: 2.7.1.105]
ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate.
  • Not identical with EC 2.7.1.11.
  • The enzyme copurifies with EC 3.1.3.46.
98 A0A060TE12 A0A061HY48 A0A061I0X0 A0A061I7E2 A0A061I832 A0A061IBE2 A0A061IDI8 A0A075AX60 A0A088RHR2 A0A0B2QNY7
(88 more...)
Fructose-2,6-bisphosphate 2-phosphatase. [EC: 3.1.3.46]
Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
  • The enzyme copurifies with EC 2.7.1.105 (cf. EC 3.1.3.54).
84 A0A060TE12 A0A088RHR2 A0A0B7F1G5 A0A0D9RT96 A0A0F8DDZ5 A0A0L1HF25 A0A0L1HGH9 A0A0L1HVM1 A0A0P4UEG9 A0A0P4UI18
(74 more...)
RNA helicase. [EC: 3.6.4.13]
ATP + H(2)O = ADP + phosphate.
  • RNA helicases utilize the energy from ATP hydrolysis to unwind RNA.
  • Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity.
  • Some helicases unwind DNA as well as RNA.
  • May be identical with EC 3.6.4.12 (DNA helicase).
2 A0A0F8B0F8 L2G1P3
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