The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 633871: Exodeoxyribonuclease V, beta subunit

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Exodeoxyribonuclease V. [EC: 3.1.11.5]
Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.
  • Preference for double-stranded DNA.
  • Possesses DNA-dependent ATPase activity.
  • Acts endonucleolytically on single-stranded circular DNA.
  • Similar enzyme: Haemophilus influenzae ATP-dependent DNase.
2985 A0A010Q5V1 A0A010SJL4 A0A011MKB6 A0A011QHQ9 A0A014PVS4 A0A014QAW9 A0A017IB11 A0A017PKF7 A0A017QHE4 A0A022PE98
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