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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 633522: Putative Pentafunctional AROM polypeptide

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-phosphoshikimate 1-carboxyvinyltransferase. [EC: 2.5.1.19]
Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O- (1-carboxyvinyl)-3-phosphoshikimate.
    		 545 A0A010RP22 A0A017S5L2 A0A022VZT9 A0A022XQ62 A0A024RVA1 A0A059J9X2 A0A060S9A7 A0A060T792 A0A061B2K6 A0A061HAC0
    (535 more...)
    Shikimate kinase. [EC: 2.7.1.71]
    ATP + shikimate = ADP + shikimate 3-phosphate.
      		 517 A0A010RP22 A0A017S5L2 A0A024RVA1 A0A059J9X2 A0A060S9A7 A0A060T792 A0A061B2K6 A0A061HAC0 A0A063BLV6 A0A066WEQ3
      (507 more...)
      3-dehydroquinate synthase. [EC: 4.2.3.4]
      3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.
      • The hydrogen atoms on C-7 of the substrate are retained on C-2 of the products.
      • Formerly EC 4.6.1.3.
      		 517 A0A010RP22 A0A017S5L2 A0A024RVA1 A0A059J9X2 A0A060S9A7 A0A060T792 A0A061B2K6 A0A061HAC0 A0A063BLV6 A0A066WEQ3
      (507 more...)
      Shikimate dehydrogenase. [EC: 1.1.1.25]
      Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
      • NAD(+) cannot replace NADP(+).
      • In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
      		 517 A0A010RP22 A0A017S5L2 A0A024RVA1 A0A059J9X2 A0A060S9A7 A0A060T792 A0A061B2K6 A0A061HAC0 A0A063BLV6 A0A066WEQ3
      (507 more...)
      3-dehydroquinate dehydratase. [EC: 4.2.1.10]
      3-dehydroquinate = 3-dehydroshikimate + H(2)O.
        		 517 A0A010RP22 A0A017S5L2 A0A024RVA1 A0A059J9X2 A0A060S9A7 A0A060T792 A0A061B2K6 A0A061HAC0 A0A063BLV6 A0A066WEQ3
        (507 more...)
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