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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 633154: Type I site-specific deoxyribonuclease

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Type I site-specific deoxyribonuclease. [EC: 3.1.21.3]
Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.
  • Large group of enzymes that have an absolute requirement for ATP (or dATP) and S-adenosyl-L-methionine.
  • They recognize specific short DNA sequences and cleave at sites remote from the recognition sequence.
  • Multifunctional proteins which also catalyze the reactions of EC 2.1.1.72 and EC 2.1.1.73, with similar site specificity.
  • Formerly EC 3.1.24.1 and EC 3.1.24.2.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
 229 A0A031G8I3 A0A031H9E7 A0A061CBB7 A0A062VCZ2 A0A066PQ98 A0A068E232 A0A076K380 A0A081FTJ7 A0A084A3G9 A0A084EZI4
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