The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 632841: ATP-dependent RNA helicase DBP5

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
RNA helicase. [EC: 3.6.4.13]
ATP + H(2)O = ADP + phosphate.
  • RNA helicases utilize the energy from ATP hydrolysis to unwind RNA.
  • Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity.
  • Some helicases unwind DNA as well as RNA.
  • May be identical with EC 3.6.4.12 (DNA helicase).
101 A0A024UYP8 A0A024VGF0 A0A024VZK8 A0A024WIL0 A0A024WZB3 A0A060S0I8 A0A077TNY5 A0A077XG50 A0A078KGJ2 A0A0D3FE14
(91 more...)
Thioredoxin-disulfide reductase. [EC: 1.8.1.9]
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
  • May be identical to EC 1.8.1.10.
  • Formerly EC 1.6.4.5.
2 R9NVR0 W3VRH6
Histone-lysine N-methyltransferase. [EC: 2.1.1.43]
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
    1 A0A1A9W2I0
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