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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 631998: ABC transporter ATP-binding protein

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 29 A0A085ABQ2 A0A085GJ48 A0A085GMY6 A0A085GQ50 A0A085H6K6 A0A085HNJ4 A0A085III1 A0A085JJN4 A0A085U356 A0A097R5R7
(19 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
 25 A0A085ABQ2 A0A085GJ48 A0A085GMY6 A0A085GQ50 A0A085H6K6 A0A085HNJ4 A0A085III1 A0A085JJN4 A0A097R5R7 A0A0H2Q9P4
(15 more...)
Phosphonate-transporting ATPase. [EC: 3.6.3.28]
ATP + H(2)O + phosphonate(Out) = ADP + phosphate + phosphonate(In).
  • A bacterial enzyme that imports phosphonate and organophosphate anions.
 11 A0A099KAI8 A0A099KLB6 A0A099LA54 A0A099LAR0 A0A0D5M5N7 A0A161UYE5 G0B0C3 G3IX63 G7LS89 V3TTP2
(1 more...)
Polyamine-transporting ATPase. [EC: 3.6.3.31]
ATP + H(2)O + polyamine(Out) = ADP + phosphate + polyamine(In).
  • A bacterial enzyme that imports putrescine and spermidine.
 10 A0A0F4T0Z5 A0A0Q6QGG3 F2K3B9 F6AGF4 F6D182 F9UEM0 G2E3J9 G4E8L9 W6VAW9 W6VXA6
Fe(3+)-transporting ATPase. [EC: 3.6.3.30]
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
  • A bacterial enzyme that imports ferric cations.
 1 A0A0U5IAS4
Phosphate-transporting ATPase. [EC: 3.6.3.27]
ATP + H(2)O + phosphate(Out) = ADP + phosphate + phosphate(In).
  • A bacterial enzyme that imports phosphate anions.
 1 Q3J7B8
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