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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 631561: Dynein heavy chain, cytoplasmic

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 54 A0A0J9RP14 A0A0J9RP19 A0A0J9RP89 A0A0J9RPM1 A0A0J9RPM6 A0A0J9RQP0 A0A0J9UET5 A0A0J9UEU2 A0A0N8P0Q9 A0A0P8XSV6
(44 more...)
Minus-end-directed kinesin ATPase. [EC: 3.6.4.5]
ATP + H(2)O = ADP + phosphate.
  • Structurally almost identical to EC 3.6.4.3 but the movement it catalyzes is toward the minus end of microtubules.
 6 M9PBQ0 M9PBQ3 M9PE73 M9PEC8 M9PEN4 M9PHG8
Dynein ATPase. [EC: 3.6.4.2]
ATP + H(2)O = ADP + phosphate.
  • A multisubunit protein complex associated with microtubules.
  • Hydrolysis of ATP provides energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome toward the microtubule's minus end.
  • It also functions in the movement of eukaryotic flagella and cilia.
  • Formerly EC 3.6.1.33.
 4 A0A0B7F7W3 A0A0F4YV18 A2RAF2 B6HJQ7
Acid phosphatase. [EC: 3.1.3.2]
A phosphate monoester + H(2)O = an alcohol + phosphate.
  • Wide specificity.
  • Also catalyzes transphosphorylations.
 2 A0A182VZ21 A0A1A9TNA0
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