The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 631044: Ribose 1,5-bisphosphate phosphokinase PhnN

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ribose 1,5-bisphosphate phosphokinase. [EC: 2.7.4.23]
ATP + alpha-D-ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate.
  • This enzyme, found in NAD suppression mutants of Escherichia coli, synthesizes 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) without the participation of EC 2.7.6.1.
  • Ribose, ribose 1-phosphate and ribose 5-phosphate are not substrates, and GTP cannot act as a phosphate donor.
13 A0A083ZXX8 A0A0D8MLE8 A0A0E9BLP4 A0A0F5F5R6 A0A0F5Y2N6 A0A0H3L4L2 A0A1F1QJH0 A0A1K1VD93 A1TX61 J2KUR2
(3 more...)
Guanylate kinase. [EC: 2.7.4.8]
ATP + GMP = ADP + GDP.
  • dGMP can also act as acceptor.
  • dATP can act as donor.
1 W1F5U2
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