The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 630745: Cell division control protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P32457 (/IPI) P32468 (/IPI) P40797 (/IPI) P48009 (/IPI) |
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
3 | P32457 (/IDA) P32468 (/IDA) P40797 (/IDA) |
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
2 | P32468 (/IDA) P40797 (/IDA) |
Structural molecule activity GO:0005198
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
|
2 | P32457 (/IDA) P32468 (/IDA) |
Phosphatidylinositol-5-phosphate binding GO:0010314
Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.
|
2 | P32457 (/IDA) P32468 (/IDA) |
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
2 | P32457 (/IDA) P32468 (/IDA) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | P40797 (/IDA) |
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
1 | P40797 (/IDA) |
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | P40797 (/IPI) |
Protein complex scaffold GO:0032947
A structural molecule activity that provides a physical support for the assembly of a multiprotein complex. The scaffold may or may not be part of the final complex.
|
1 | P32468 (/IMP) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P40797 (/IDA) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
4 | P32457 (/IMP) P32468 (/IMP) P40797 (/IMP) P48009 (/IMP) |
Septin ring assembly GO:0000921
The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
|
3 | A0A1D8PCY5 (/IMP) P32457 (/IMP) P32468 (/IMP) |
Maintenance of cell polarity GO:0030011
The maintenance of established anisotropic intracellular organization or cell growth patterns.
|
2 | A0A1D8PCY5 (/IMP) P32468 (/IMP) |
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | P32457 (/IDA) |
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | P40797 (/ISS) |
Actomyosin contractile ring assembly GO:0000915
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
1 | P40797 (/NAS) |
Cell separation after cytokinesis GO:0000920
The process of physically separating progeny cells after cytokinesis; this may involve enzymatic digestion of septum or cell wall components.
|
1 | A0A1D8PCY5 (/IMP) |
Septin ring assembly GO:0000921
The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
|
1 | P32468 (/IDA) |
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
1 | P40797 (/IGI) |
Cellularization GO:0007349
The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.
|
1 | P40797 (/TAS) |
Maintenance of cell polarity GO:0030011
The maintenance of established anisotropic intracellular organization or cell growth patterns.
|
1 | P32457 (/IC) |
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
|
1 | C8V1M3 (/IMP) |
Septin ring disassembly GO:0031107
The controlled breakdown of a septin ring.
|
1 | P32457 (/IMP) |
Cellular protein localization GO:0034613
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
|
1 | P48009 (/IMP) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | P40797 (/IDA) |
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
1 | P32468 (/IDA) |
Conidiophore development GO:0070787
The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
|
1 | C8V1M3 (/IMP) |
There are 27 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cellular bud neck septin ring GO:0000144
A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.
|
4 | A0A1D8PCY5 (/IDA) A0A1D8PD83 (/IDA) P32457 (/IDA) P32468 (/IDA) |
Septin complex GO:0031105
A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric.
|
4 | P32457 (/IDA) P32468 (/IDA) P40797 (/IDA) P48009 (/IDA) |
Septin ring GO:0005940
A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.
|
3 | A0A1D8PCY5 (/IDA) A0A1D8PD83 (/IDA) P48009 (/IDA) |
Septin complex GO:0031105
A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric.
|
3 | P32457 (/IPI) P32468 (/IPI) P40797 (/IPI) |
Incipient cellular bud site GO:0000131
The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
|
2 | A0A1D8PCY5 (/IDA) A0A1D8PD83 (/IDA) |
Mating projection base GO:0001400
The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.
|
2 | A0A1D8PCY5 (/IDA) P32457 (/IDA) |
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
|
2 | A0A1D8PCY5 (/IDA) A0A1D8PD83 (/IDA) |
Septin ring GO:0005940
A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.
|
2 | A0A1D8PCY5 (/IPI) A0A1D8PD83 (/IPI) |
Cell septum GO:0030428
A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
|
2 | A0A1D8PCY5 (/IDA) A0A1D8PD83 (/IDA) |
Septin filament array GO:0032160
Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans.
|
2 | P32457 (/IDA) P32468 (/IDA) |
Cellular bud neck septin ring GO:0000144
A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.
|
1 | A0A1D8PD83 (/IGI) |
Hyphal tip GO:0001411
The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
|
1 | A0A1D8PD83 (/IDA) |
Ascospore wall GO:0005619
The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.
|
1 | P32457 (/IDA) |
Cellular bud scar GO:0005621
Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.
|
1 | P32468 (/IDA) |
Prospore membrane GO:0005628
The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
|
1 | P32457 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | C8V1M3 (/IDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | P40797 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P48009 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P40797 (/IDA) |
Mating projection GO:0005937
The projection formed by unicellular fungi in response to mating pheromone.
|
1 | P32468 (/IDA) |
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
1 | A0A1D8PCY5 (/IDA) |
Septin ring GO:0005940
A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.
|
1 | P40797 (/ISS) |
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | P48009 (/IDA) |
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
|
1 | P40797 (/IDA) |
Hyphal septin ring GO:0032168
A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.
|
1 | C8V1M3 (/IDA) |
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
|
1 | P40797 (/IDA) |
Contractile ring GO:0070938
A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.
|
1 | P40797 (/IDA) |