The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 630731: Interferon-gamma-inducible GTPase Ifggb5 protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q62293 (/IDA) Q9QZ85 (/IDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q9QZ85 (/ISS)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 Q9QZ85 (/IDA)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
1 Q9QZ85 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9QZ85 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to interferon-beta GO:0035458
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
3 Q3UED7 (/IDA) Q62293 (/IDA) Q9QZ85 (/IDA)
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
1 Q61635 (/IMP)
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
1 Q62293 (/NAS)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
1 Q62293 (/IDA)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 Q9QZ85 (/IMP)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q9QZ85 (/TAS)
Response to interferon-gamma GO:0034341
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
1 Q62293 (/IDA)
Response to interferon-alpha GO:0035455
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.
1 Q62293 (/IDA)
Defense response to protozoan GO:0042832
Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.
1 Q9QZ85 (/IDA)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 Q9QZ85 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 Q62293 (/NAS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q61635 (/TAS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q9QZ85 (/IDA)
Symbiont-containing vacuole membrane GO:0020005
The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.
1 Q9QZ85 (/IDA)
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