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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 630178: Amino acid ABC transporter ATPase

There are 9 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Fe(3+)-transporting ATPase. [EC: 3.6.3.30]
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
  • A bacterial enzyme that imports ferric cations.
 41 A0A072MVE1 A0A075KJ15 A0A083XY50 A0A0C2BYX0 A0A0E9LIF1 A0A0L6JPU7 A0A0M1QI22 A0A0N1FNH7 A0A0N1FWY3 A0A0N1GKM7
(31 more...)
Phosphate-transporting ATPase. [EC: 3.6.3.27]
ATP + H(2)O + phosphate(Out) = ADP + phosphate + phosphate(In).
  • A bacterial enzyme that imports phosphate anions.
 41 A0A062WL70 A0A064BVF7 A0A081PSB3 A0A081Q3P1 A0A081V4P8 A0A095X2B4 A0A0B7L493 A0A0C1K5E6 A0A0H2UP95 A0A0H2ZPS6
(31 more...)
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 36 A0A085HQX9 A0A085I7D2 A0A091BTV0 A0A0E2BVI2 A0A0R1EYA7 A0A125YCS5 A0A198GFA9 A0A1B7HRH6 A0A1B7ICM0 A0A1B7IPF7
(26 more...)
Phosphonate-transporting ATPase. [EC: 3.6.3.28]
ATP + H(2)O + phosphonate(Out) = ADP + phosphate + phosphonate(In).
  • A bacterial enzyme that imports phosphonate and organophosphate anions.
 19 A0A074J528 A0A0E0UG28 A0A150FNC7 A0A1B9VKU7 A0A1N7MYL9 F2JQQ6 F6BIC7 F6CPZ9 F7X5Q8 F8F0C9
(9 more...)
Sulfate-transporting ATPase. [EC: 3.6.3.25]
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
  • A bacterial enzyme that imports sulfate and thiosulfate anions.
 18 A0A031H0C1 A0A083ZSE8 A0A087B7C0 A0A087BJN4 A0A087D226 A0A087DYG1 A0A087E2R0 A0A087EF17 A0A087EKP1 A0A174PDM6
(8 more...)
Monosaccharide-transporting ATPase. [EC: 3.6.3.17]
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).
  • Family of bacterial enzymes importing ribose, xylose, arabinose, galactose and methylgalactoside.
 16 A0A031HK23 A0A063BFU7 A0A087BSY3 A0A087D7K0 A0A0E9LH76 E8TYJ0 F2NCH6 F4GD02 F5UDI2 F6B0K9
(6 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
 9 A0A085HQX9 A0A085I7D2 A0A091BTV0 A0A198GFA9 A0A1B7HRH6 A0A1B7ICM0 A0A1B7IPF7 A0A1B7K1C6 G2SAJ9
Polyamine-transporting ATPase. [EC: 3.6.3.31]
ATP + H(2)O + polyamine(Out) = ADP + phosphate + polyamine(In).
  • A bacterial enzyme that imports putrescine and spermidine.
 9 A0A086ZKL3 A0A087DM76 A0A087DX02 A0A0G9MBP3 A1A0J5 A7A4G7 F2LWQ0 K4Q895 R5GRP9
Nonpolar-amino-acid-transporting ATPase. [EC: 3.6.3.22]
ATP + H(2)O + nonpolar amino acid(Out) = ADP + phosphate + nonpolar amino acid(In).
  • Comprises bacterial enzymes that import Leu, Ile and Val.
 4 A0A1K0JB72 G0ERL0 Q0K8G7 R7X9T0
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