The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 629266: ABC transporter, ATP-binding protein

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Heme-transporting ATPase. [EC: 3.6.3.41]
ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out).
  • An enzyme found in Gram-negative bacteria that exports heme.
97 A0A026V6F7 A0A027ZR74 A0A028E0F7 A0A029KU93 A0A029PNS3 A0A062YCP8 A0A070CH16 A0A070KIV0 A0A070SLR1 A0A070V029
(87 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
9 A0A085AB84 A0A085G1M9 A0A085GIT7 A0A085HDL8 A0A198H0Y6 A0A1B7HKJ4 A0A1B7I2K9 A0A1B7II83 G2SC95
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
9 A0A085AB84 A0A085G1M9 A0A085GIT7 A0A085HDL8 A0A198H0Y6 A0A1B7HKJ4 A0A1B7I2K9 A0A1B7II83 G2SC95
Monosaccharide-transporting ATPase. [EC: 3.6.3.17]
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).
  • Family of bacterial enzymes importing ribose, xylose, arabinose, galactose and methylgalactoside.
9 A0A0A0FF90 A0A0A0G4K4 A0A0A0H2G4 A0A1K3B454 C8T5E4 F5S253 R4YI19 S1IKG7 V3TPU6
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