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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 627362: Adenylate kinase 8

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenylate kinase. [EC: 2.7.4.3]
ATP + AMP = 2 ADP.
  • Inorganic triphosphate can also act as donor.
 6 Q32M07 Q4R3W4 Q5M7G4 Q68FP8 Q6P618 Q96MA6
Nucleoside-diphosphate kinase. [EC: 2.7.4.6]
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
  • Many nucleoside diphosphates can act as acceptors.
  • Many ribo- and deoxyribonucleoside triphosphates can act as donors.
 6 Q32M07 Q4R3W4 Q5M7G4 Q68FP8 Q6P618 Q96MA6
RNA helicase. [EC: 3.6.4.13]
ATP + H(2)O = ADP + phosphate.
  • RNA helicases utilize the energy from ATP hydrolysis to unwind RNA.
  • Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity.
  • Some helicases unwind DNA as well as RNA.
  • May be identical with EC 3.6.4.12 (DNA helicase).
 1 A0A091DLH2
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