The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 621732: ABC transporter ATP-binding protein

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Heme-transporting ATPase. [EC: 3.6.3.41]
ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out).
  • An enzyme found in Gram-negative bacteria that exports heme.
161 A0A017IJ93 A0A024KR66 A0A026RSD4 A0A026UTD3 A0A027U719 A0A028E7W4 A0A029I8N0 A0A029IYS8 A0A029KYS3 A0A029LUZ1
(151 more...)
Fe(3+)-transporting ATPase. [EC: 3.6.3.30]
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
  • A bacterial enzyme that imports ferric cations.
127 A0A024KR66 A0A026RSD4 A0A026UTD3 A0A027U719 A0A028E7W4 A0A029I8N0 A0A029IYS8 A0A029KYS3 A0A029LUZ1 A0A029PSW6
(117 more...)
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
28 A0A084ZU64 A0A085G984 A0A085GJX6 A0A085GR18 A0A085H446 A0A085HMZ3 A0A085IH97 A0A085JC49 A0A085U4B0 A0A097R4K3
(18 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
26 A0A084ZU64 A0A085G984 A0A085GJX6 A0A085GR18 A0A085H446 A0A085HMZ3 A0A085IH97 A0A085JC49 A0A097R4K3 A0A0B8ZMA2
(16 more...)
Iron-chelate-transporting ATPase. [EC: 3.6.3.34]
ATP + H(2)O + iron chelate(Out) = ADP + phosphate + iron chelate(In).
  • A bacterial enzyme that imports Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores.
2 A0A1B1NP92 F9RU00
Sulfate-transporting ATPase. [EC: 3.6.3.25]
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
  • A bacterial enzyme that imports sulfate and thiosulfate anions.
1 Q3IGN6
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