The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 620279: ABC transporter, ATP-binding protein

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
18 A0A084ZSB0 A0A085G1V4 A0A085GPG1 A0A085HDW0 A0A085ILV3 A0A085UAR3 A0A0N0ZD01 A0A198FPN4 A0A198GYJ9 A0A1B7HKI4
(8 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
16 A0A084ZSB0 A0A085G1V4 A0A085GPG1 A0A085HDW0 A0A085ILV3 A0A0N0ZD01 A0A198FPN4 A0A198GYJ9 A0A1B7HKI4 A0A1B7I2T3
(6 more...)
Fe(3+)-transporting ATPase. [EC: 3.6.3.30]
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
  • A bacterial enzyme that imports ferric cations.
6 A0A031GAV2 A0A0C2R555 A0A1A9JCN9 K0WBA1 W6UV44 W6VIX9
Sulfate-transporting ATPase. [EC: 3.6.3.25]
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
  • A bacterial enzyme that imports sulfate and thiosulfate anions.
3 F6AEY6 G8Q9D8 Q1IEA6
3-deoxy-manno-octulosonate-8-phosphatase. [EC: 3.1.3.45]
3-deoxy-D-manno-octulosonate 8-phosphate + H(2)O = 3-deoxy-D-manno- octulosonate + phosphate.
    1 G8Q9D8
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