View in Gene3D

CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 22148: Type III restriction enzyme, res subunit

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Type III site-specific deoxyribonuclease. [EC: 3.1.21.5]
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
  • Has an absolute requirement for ATP, but does not hydrolyze it; S-adenosyl-L-methionine stimulates the reaction, but is not absolutely required.
  • Recognize specific short DNA sequences and cleave a short distance away from the recognition sequence.
  • Exist as complexes with enzymes of similar specificity listed under EC 2.1.1.72 or EC 2.1.1.73.
  • Formerly EC 3.1.24.3 and EC 3.1.24.4.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
 12 A0A0H5Q925 A0A0P1CZH7 A0A0Y5SWX0 A0A0Y6Q3Y5 A0A0Y7LU85 A0A125WD98 C6S7L1 E3D5X1 I4E4Z4 J8T530
(2 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...