The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 208222: Monofunctional C1-tetrahydrofolate synthase, mitoc...
There are 3 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
Formate--tetrahydrofolate ligase.
[EC: 6.3.4.3]
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
|
17 |
A0A136KZF0
A0A1F8KGL5
A0A1F8QGM2
A0A1J4ZW45
B9T077
B9T079
E0VA04
I0I5C6
P11586
P27653 (7 more...) |
|
Methylenetetrahydrofolate dehydrogenase (NADP(+)).
[EC: 1.5.1.5]
5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
|
9 | A0A061HZ51 A0A0B2QZH4 A0A0B2RSC0 E0VA04 G3H4Z5 P11586 P27653 Q5R8P0 Q922D8 |
|
Methenyltetrahydrofolate cyclohydrolase.
[EC: 3.5.4.9]
5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
|
6 | A0A0B2QZH4 A0A0B2RSC0 P11586 P27653 Q5R8P0 Q922D8 |
