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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 180797: Type III restriction endonuclease StyLTI

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Type III site-specific deoxyribonuclease. [EC: 3.1.21.5]
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
  • Has an absolute requirement for ATP, but does not hydrolyze it; S-adenosyl-L-methionine stimulates the reaction, but is not absolutely required.
  • Recognize specific short DNA sequences and cleave a short distance away from the recognition sequence.
  • Exist as complexes with enzymes of similar specificity listed under EC 2.1.1.72 or EC 2.1.1.73.
  • Formerly EC 3.1.24.3 and EC 3.1.24.4.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
 13 A0A0F7J6K9 A0A0G2NJD5 A0A0H3BKJ4 A0A0J6DF92 A0A0N1QVX3 A0A0R9Q249 A0A0U1K3C2 A0A1L3M9K0 B3YB49 B5EWN9
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