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CATH Superfamily 3.40.50.2000

Glycogen Phosphorylase B;

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Glycogen Phosphorylase B;
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 95419: Sucrose synthase isoform 4

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sucrose synthase. [EC: 2.4.1.13]
NDP-glucose + D-fructose = NDP + sucrose.
  • Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose.
  • Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP- glucose (necessary for starch biosynthesis).
 2060 A0A022PU65 A0A022PU65 A0A022QGY2 A0A022QGY2 A0A022RF08 A0A022RF08 A0A022S1V3 A0A022S1V3 A0A022S467 A0A022S467
(2050 more...)
Sucrose-phosphate synthase. [EC: 2.4.1.14]
UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6(F)-phosphate.
  • The enzyme from Synechocystis sp. strain PCC 6803 is not specific for UDP-glucose as it can use ADP-glucose and, to a lesser extent, GDP- glucose as substrates.
  • The enzyme from rice leaves is activated by glucose 6-phosphate but that from cyanobacterial species is not.
  • While the reaction catalyzed by this enzyme is reversible, the enzyme usually works in concert with EC 3.1.3.24 to form sucrose, making the above reaction essentially irreversible.
  • The F in sucrose 6(F)-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.
 4 O24302 O24302 V5V2Y3 V5V2Y3
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