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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115265: Bile salt-dependent lipase oncofetal isoform

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Carboxylesterase. [EC: 3.1.1.1]
A carboxylic ester + H(2)O = an alcohol + a carboxylate.
  • Wide specificity; also hydrolyzes vitamin A esters.
  • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
  • Formerly EC 3.1.1.12.
 14 E0VEL7 E0VEL7 M9NCS8 M9NCS8 P33438 P33438 Q04456 Q04456 Q04457 Q04457
(4 more...)
Triacylglycerol lipase. [EC: 3.1.1.3]
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
  • The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
 10 P07882 P07882 P19835 P19835 P30122 P30122 Q3V2H7 Q3V2H7 Q64285 Q64285
Sterol esterase. [EC: 3.1.1.13]
A steryl ester + H(2)O = a sterol + a fatty acid.
  • A group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols.
  • Activated by bile salts.
 10 P07882 P07882 P19835 P19835 P30122 P30122 Q3V2H7 Q3V2H7 Q64285 Q64285
Juvenile-hormone esterase. [EC: 3.1.1.59]
(1) Juvenile hormone I + H(2)O = juvenile hormone I acid + methanol. (2) Juvenile hormone III + H(2)O = juvenile hormone III acid + methanol.
  • Demethylates the insect juvenile hormones, JH1 and JH3, but does not hydrolyze the analogous ethyl or isopropyl esters.
 2 P12992 P12992
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