The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Formyl transferase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6017: Putative 10-formyltetrahydrofolate dehydrogenase A...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Formyltetrahydrofolate dehydrogenase. [EC: 1.5.1.6]
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
    205 A0A026WU32 A0A060XXQ4 A0A060Y3G7 A0A061IGK4 A0A087XFM4 A0A087ZYB7 A0A096N2X9 A0A0B2VES1 A0A0B6ZYE6 A0A0C2H4K2
    (195 more...)
    Methionyl-tRNA formyltransferase. [EC: 2.1.2.9]
    10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).
      33 A0A045GRX6 A0A083VTD9 A0A089NYQ8 A0A0H3LFQ5 A0A0H3M919 A0A0K2I1A8 A0A0R0LKP3 A0A0S8I2V1 A0A0T9B3I7 A0A109T0R4
      (23 more...)
      Aldehyde dehydrogenase (NAD(+)). [EC: 1.2.1.3]
      An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
      • Wide specificity, including oxidation of D-glucuronolactone to D-glucarate.
      • Formerly EC 1.1.1.70.
      1 V4TLP7
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