CATH Superfamily 3.30.450.20

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
87831	Nitrogen regulation protein NR II	34984	EC		-	-	88.5
87759	Lipoate-protein ligase A	27851	EC		-	-	55.6
87597	Aerobic respiration control sensor protein	22646	EC		-	-	80.2
87882	PAS sensor histidine kinase	7387	EC	3D	4gczA01	-	88.6
87764	DNA-binding transcriptional regulator TyrR	7207		3D	2jheA02	-	19.2
87607	Phosphate regulon sensor protein	7010	EC		-	-	35.3
34695	Sensor histidine kinase DpiB	6000	EC		-	-	26.0
66488	Sensor histidine kinase DpiB	6000	EC		-	-	18.6
63498	Sensory histidine kinase DcuS	5137	EC	3D	2w0nA00	-	40.3
16048	Sensor histidine kinase DcuS	4775	EC	3D	1ojgA00	-	24.1
18423	Putative two-component sensor kinase	3778	EC		-	-	60.8
88161	Sensor histidine kinase RcsC	3000	EC		-	-	97.1
87880	Putative sensor protein ZraS	2796	EC		-	-	74.7
88050	Sensor protein kinase walK	2738	EC	3D	5is1A00	-	99.3
87716	Sensor protein kinase WalK	2572	EC	3D	4mn5A00	-	61.6
88047	Putative sigma-54-dependent transcriptional regulator YgeV	2303	EC		-	-	73.0
87869	Hypoxia-inducible factor 1 alpha	1951	EC		-	-	89.0
32795	RNase II stability modulator	1676	EC		-	-	78.5
40488	Putative diguanylate cyclase YdaM	1514	EC		-	-	53.1
87784	Aryl hydrocarbon receptor nuclear translocator	1369	EC	3D	4f3lB02	-	83.1
32689	Histidine kinase	1295	EC		-	-	13.0
87646	Oxygen sensor histidine kinase NreB	1242	EC		-	-	71.6
87594	Histidine kinase	1102	EC		-	-	54.0
88138	Putative antitoxin module of toxin-antitoxin system	884		3D	2h28A01	-	82.9
87790	Hypoxia-inducible factor 1 alpha	815		3D	4h6jA00	-	86.4
88033	Sensory box sensor histidine kinase PhoR	791	EC		-	-	98.5
87805	Putative photoreceptor phytochrome	761	EC		-	-	84.0
87718	Circadian locomoter output cycles protein kaput	747	EC	3D	4f3lA03	-	82.6
56674	Heme-regulated cyclic AMP phosphodiesterase	727	EC	3D	1s66L00	-	30.7
36889	Heme-regulated cyclic AMP phosphodiesterase	713	EC		-	-	41.8
87883	Period circadian protein homolog 1	698		3D	3gdiA02	-	81.9
87786	Putative phytochrome A	660			-	-	98.8
87866	Aryl hydrocarbon receptor nuclear translocator-like	629	EC	3D	4f3lB03	-	95.3
14382	His Kinase A domain protein	628	EC		-	-	8.8
87900	Voltage-dependent calcium channel subunit alpha-2/delta-2	626			-	-	90.5
87750	Aryl hydrocarbon receptor 1	606			-	-	89.8
87712	Nuclear receptor coactivator 2	564	EC		-	-	87.9
87876	Circadian locomoter output cycles protein kaput	562	EC	3D	4f3lA02	-	94.8
87779	Period circadian protein-like 1	557		3D	3gdiA01	-	92.7
87793	Potassium voltage-gated channel protein eag	497		3D	5j7eA00	-	88.6
87775	Aryl hydrocarbon receptor 1B	486		3D	4m4xA00	-	88.0
46842	Single-minded homolog 2	473	EC		-	-	75.1
87903	Methyl-accepting chemotaxis sensory transducer	462	EC		-	-	99.5
87722	Aryl hydrocarbon receptor nuclear translocator	455		3D	1x0oA01	-	85.5
87813	Potassium channel erg1a	444		3D	1bywA00	-	83.6
68480	PAS fold family protein	398			-	-	27.3
87913	PAS/PAC sensor signal transduction histidine kinase	395	EC	3D	1d06A00	-	97.9
88085	White collar 1 protein	377	EC		-	-	95.1
88071	Phosphoenolpyruvate-dihydroxyacetone phosphotransferase operon regulatory protein DhaR	346	EC	3D	4lrxC02	-	97.2
87717	Period circadian protein	317			-	-	96.8
88046	Probable diguanylate cyclase YegE	308	EC		-	-	92.5
87846	Sensory box histidine kinase FleS	306	EC		-	-	89.8
28712	Sensor kinase DpiB	304	EC	3D	1p0zA00	-	33.1
88096	Nuclear receptor coactivator 2	276	EC		-	-	89.4
87657	Neuronal PAS domain-containing protein 3	225			-	-	86.9
87878	Neuronal PAS domain-containing protein 4	187			-	-	93.1
87976	White collar 1 protein	172			-	-	82.4
67850	Sensor protein, histidine kinase	164	EC		-	-	88.5
87904	Nitrogen regulation protein NtrB	163	EC		-	-	96.6
81405	Histidine kinase	163	EC		-	-	82.9
50405	Histidine kinase	149	EC		-	-	12.9
30715	Histidine kinase	148	EC		-	-	0.0
87787	Putative circadian clock protein period	141		3D	1wa9A02	-	84.7
69942	VWFA and cache domain-containing protein 1	140			-	-	50.7
32688	Two component sensor kinase	138	EC		-	-	0.0
87641	IBMX-insensitive phosphodiesterase 8B	133	EC		-	-	74.1
87872	Methyl-accepting chemotaxis protein	132			-	-	90.8
87707	Aryl hydrocarbon receptor repressor	131			-	-	75.8
87755	Period circadian protein	130			-	-	87.2
21582	Probable diguanylate cyclase YegE	127	EC		-	-	7.0
34317	Multi-sensor signal transduction histidine kinase	125	EC		-	-	43.2
87659	Protein Pde8a	120	EC		-	-	71.2
87801	Transcription activator of gluconeogenesis ERT1-2	118			-	-	88.8
87767	Sigma-54 dependent transcriptional regulator PhhR	117			-	-	73.5
87614	Similar to uniprot\|P19541 Saccharomyces cerevisiae YPL133c	115			-	-	61.7
87893	Methyl-accepting chemotaxis protein McpA	108			-	-	87.5
69973	Sensor protein SrrB	106	EC		-	-	14.0
87873	Voltage-dependent calcium channel subunit alpha-2/delta-4	105			-	-	77.4
10135	VWFA and cache domain-containing protein 1	101			-	-	36.3
63559	Nuclear receptor coactivator 1	99	EC	3D	1oj5A00	-	38.1
50241	Sensor histidine kinase	98	EC		-	-	1.1
78195	N-linked glycosylation glycosyltransferase PglG	97			-	-	0.0
55126	Sensor histidine kinase CitA	92	EC		-	-	16.7
87863	Methyl-accepting chemotaxis protein TlpB	92			-	-	87.6
87884	Methyl-accepting chemotaxis protein PctC	90			-	-	88.9
59341	Methyl-accepting chemotaxis protein	87			-	-	23.8
81006	Methyl-accepting chemotaxis MCP	84			-	-	11.7
6867	Voltage-dependent calcium channel subunit alpha-2/delta-3	82			-	-	24.5
87820	Probable C4-dicarboxylate sensor kinase	79	EC		-	-	67.0
36182	Alkaline phosphatase synthesis sensor protein PhoR	78	EC		-	-	21.4
87669	Neuronal PAS domain-containing protein 1	74			-	-	38.9
7686	Potassium voltage-gated channel subfamily H member 4	70			-	-	49.2
87782	Chemotactic transducer PctB	67			-	-	74.2
87715	Photoactive yellow protein	67		3D	1d7eA00	-	47.3
87649	Autoinducer 2 sensor kinase/phosphatase LuxQ	66	EC		-	-	42.0
87765	Period circadian protein	64		3D	1wa9A01	-	70.9
87604	Two-component response regulator CreC	64	EC		-	-	31.8
87778	Histidine kinase	63	EC		-	-	55.3
800	Methyl-accepting chemotaxis protein	61			-	-	45.8
71934	Voltage-dependent calcium channel subunit alpha-2/delta-1	59			-	-	39.7
60012	Potassium voltage-gated channel subfamily H member 8	57			-	-	32.7
87849	Neuronal PAS domain-containing protein 4	56			-	-	58.9
195	Histidine kinase	55	EC		-	-	6.7
50446	Histidine kinase	53	EC	3D	3by9A02	-	72.7
52000	Alkaline phosphatase synthesis sensor protein PhoR	51	EC	3D	3cwfA00	-	12.7
6449	Sensory box/GGDEF family protein	50			-	-	0.0
65482	Methyl-accepting chemotaxis protein	49			-	-	0.0
262	Histidine kinase	49	EC		-	-	0.0
56593	NifA/NtrC family transcriptional regulator	49			-	-	0.0
69132	Sensor histidine kinase	48	EC		-	-	10.6
4156	Voltage-dependent calcium channel subunit alpha-2/delta-1	48			-	-	39.1
11100	Sporulation kinase C	46	EC		-	-	2.5
30695	Histidine kinase	45	EC		-	-	10.8
19987	Sensor histidine kinase	44	EC		-	-	7.9
21555	Toxin coregulated pilus biosynthesis protein I	42			-	-	3.1
14380	Cell-division control histidine kinase PdhS	42	EC		-	-	4.1
33114	Histidine kinase	41	EC		-	-	1.9
60713	Transcriptional regulator LuxR family	41			-	-	24.4
13892	Methyl-accepting chemotaxis protein III	38			-	-	0.0
28713	Autoinducer 2 sensor kinase/phosphatase LuxQ	38	EC		-	-	9.4
34898	Methyl-accepting chemotaxis protein III	37			-	-	9.9
77671	Phosphodiesterase 8, isoform O	36	EC		-	-	26.6
87665	Transcription activator of gluconeogenesis ERT1	34			-	-	44.5
29050	Sigma L-dependent transcriptional regulator YqiR	34	EC		-	-	9.7
41600	Histidine kinase	31	EC		-	-	3.4
87676	PAS domain-containing serine/threonine-protein kinase	31	EC	3D	1ll8A00	-	24.2
69131	Phosphate regulon sensor protein PhoR	30	EC		-	-	7.9
47023	Similar, isoform B	30			-	-	46.3
5045	Sensory box sensor histidine kinase/response regulator	30	EC		-	-	17.6
77885	Sporulation kinase A	30	EC		-	-	3.4
79397	Histidine kinase	30	EC		-	-	16.6
65464	Sensor protein CitS	29	EC		-	-	7.8
70672	C4-dicarboxylate sensor kinase	29	EC		-	-	3.7
23300	Motility regulator	29	EC		-	-	0.0
28715	Histidine kinase	28	EC		-	-	0.0
14386	Methyl-accepting chemotaxis protein	27			-	-	0.7
70029	Dysfusion, isoform B	27			-	-	23.5
23881	Motility regulator	26	EC		-	-	0.0
20520	Motility regulator	26	EC		-	-	0.0
1124	Histidine kinase	26	EC		-	-	3.7
58009	Motility regulator	26	EC		-	-	0.0
20530	Sensor protein CitS	26	EC		-	-	10.3
36658	Sigma L-dependent transcriptional regulator YqiR	26	EC		-	-	0.0
75592	Cache sensor-containing chemotaxis sensory transducer	26			-	-	2.2
77895	Methyl-accepting chemotaxis protein	25			-	-	0.0
8301	Histidine kinase	25	EC		-	-	0.0
1358	Methyl-accepting chemotaxis MCP	25			-	-	0.0
67450	Methyl-accepting chemotaxis protein	25			-	-	0.0
15714	Germ cell-expressed bHLH-PAS, isoform C	25			-	-	25.0
59376	Sensory box/GGDEF family protein	23	EC		-	-	0.0
79052	Sensory box/GGDEF family protein	22	EC		-	-	0.0
75682	Eag-like K[+] channel, isoform A	21			-	-	3.3
29153	Tango, isoform B	20			-	-	33.1
20106	Sensory box sensor histidine kinase/response regulator VieS	20	EC		-	-	1.8
87907	Methyl-accepting chemotaxis MCP	19			-	-	65.0
1148	Sensor histidine kinase	19			-	-	35.6
71319	Methyl-accepting chemotaxis protein	19			-	-	7.1
40834	Sensory box/GGDEF family protein	19	EC		-	-	9.0
69134	AraC family transcriptional regulator	18			-	-	7.4
87919	Hybrid signal transduction histidine kinase L	18	EC	3D	2gj3A00	-	44.5
40835	Sensory box/GGDEF family protein	18	EC		-	-	1.1
2510	Virulence sensor protein BvgS	17	EC		-	-	18.9
88077	Drug sensory protein A	17	EC		-	-	85.3
34829	Methyl-accepting chemotaxis protein	17			-	-	5.3
76705	Methyl-accepting chemotaxis protein TlpA	17			-	-	7.3
5558	Anti-anti-sigma factor	16			-	-	0.0
76232	VWFA and cache domain-containing protein CG16868	16			-	-	32.3
64378	Methyl-accepting chemotaxis protein	16			-	-	0.0
74215	Methyl-accepting chemotaxis protein	16			-	-	0.0
13216	Histidine kinase	16	EC		-	-	0.0
47032	Accessory colonization factor AcfB	16			-	-	0.0
39077	Sensory box/GGDEF family protein	15	EC		-	-	5.2
53660	Cyclic di-GMP phosphodiesterase Gmr	15	EC		-	-	19.5
87812	Methyl-accepting chemotaxis protein	14			-	-	58.5
3817	Histidine kinase 5	13	EC		-	-	16.5
51998	Similar, isoform D	12			-	-	4.7
47427	Signaling protein YkoW	12	EC		-	-	3.8
6191	Cyclic di-GMP phosphodiesterase Gmr	12	EC		-	-	24.5
70939	AraC family transcriptional regulator	12	EC		-	-	6.5
88007	Signal transduction histidine kinase	11	EC		-	-	97.6
88037	Transcriptional regulator, LytR/AlgR family	11			-	-	86.0
73184	Methyl-accepting chemotaxis protein	11		3D	3c8cA02	-	3.2
5551	Nitrogen fixation regulatory protein	10	EC		-	-	0.0
8287	Single-minded, isoform C	9			-	-	7.0
87601	Sensor histidine kinase/response regulator Fos-1/TcsA	8	EC		-	-	41.3
14725	VWFA and cache domain-containing protein 1	8			-	-	13.2
87687	Photoactive yellow protein	8			-	-	20.1
43412	Circadian locomoter output cycles protein kaput	7			-	-	1.6
87691	Germ cell-expressed bHLH-PAS, isoform C	6			-	-	8.0
77296	Related to transcriptional regulator rds2	6			-	-	6.1
65472	Methyl-accepting chemotaxis protein	5			-	-	0.0
6889	Phytochrome 2	5			-	-	45.0
74732	GE14356	5			-	-	3.0
74216	Transcriptional regulator PpsR	5			-	-	0.0
87744	Methyl-accepting chemotaxis protein PctC	5			-	-	27.6
87697	Uncharacterized protein	5			-	-	14.2
73726	Transcriptional regulator PpsR	5			-	-	0.0
41324	Sensor histidine kinase/response regulator Fos-1	5			-	-	10.3
40718	Methyl-accepting chemotaxis sensory transducer	5			-	-	4.6
83261	Helix-loop-helix 34	4			-	-	14.1
87921	Uncharacterized protein	4			-	-	0.0
6496	Methyl-accepting chemotaxis sensory transducer	4			-	-	0.0
66688	Aryl hydrocarbon receptor protein 1	4			-	-	11.4
65465	Sensor protein DivL	4	EC		-	-	0.0
75003	Putative diguanylate cyclase	4			-	-	0.0
74214	Potassium voltage-gated channel subfamily H member 3	4			-	-	6.8
58932	Histidine kinase	4	EC		-	-	2.2
25074	Transducer protein Htr9	4			-	-	0.0
53625	Uncharacterized signaling protein CC_0091	4			-	-	0.0
88125	Transducer protein CosT	4			-	-	0.0
88105	Hybrid signal transduction histidine kinase F	3	EC		-	-	65.3
56406	Methyl-accepting chemotaxis sensory transducer	3			-	-	24.2
87814	Voltage-dependent calcium channel subunit alpha-2/delta-3	3			-	-	0.0
76624	Aryl hydrocarbon receptor protein 1	3			-	-	6.0
87830	Probable C4-dicarboxylate sensor kinase	2	EC		-	-	40.5
17018	Developmental regulator MorA	2			-	-	6.0
81382	Transcriptional regulator AcoR	2			-	-	0.0
87847	Nitrogen regulation protein NtrY	2	EC		-	-	36.2
78872	Transcriptional regulatory protein TyrR	2			-	-	0.0
3053	Hybrid signal transduction histidine kinase D	2	EC		-	-	1.9
14383	Uncharacterized sensor-like histidine kinase ycf26	2	EC		-	-	7.0
71935	CRE-HIF-1 protein	2			-	-	0.0
9138	C4-dicarboxylate transport sensor protein DctS	2	EC		-	-	0.0
13218	Hybrid signal transduction histidine kinase B	2	EC		-	-	7.2
23261	Hybrid signal transduction protein dokA	2			-	-	5.8
34697	Heme-containing CO-sensing transcriptional regulator RcoM 1	2			-	-	12.8
63688	Methyl-accepting chemotaxis sensory transducer	2			-	-	15.9
45632	Histidine kinase	2	EC		-	-	20.3
15621	Uncharacterized sensor-like histidine kinase R01002	2	EC		-	-	10.9
42773	Methyl-accepting chemotaxis protein	1			-	-	0.0
68337	Two-component system protein A	1	EC		-	-	0.0
85430	Nitrogen fixation regulatory protein	1			-	-	0.0
63709	Energy taxis modulating methyl accepting sensory transducer	1			-	-	0.0
72192	Uncharacterized protein	1			-	-	0.0
59330	Signal-transduction histidine kinase senX3	1	EC		-	-	0.0
54360	Methyl-accepting chemotaxis sensory transducer	1			-	-	0.0
74713	Glucose starvation modulator protein 1	1			-	-	0.0
44051	Sensor protein SphS	1	EC		-	-	0.0
15974	GL22009	1			-	-	0.0
77884	Helix-loop-helix 34	1			-	-	0.0
32690	Histidine protein kinase DivJ	1	EC		-	-	0.0
87843	Glucose starvation modulator protein 1	1			-	-	0.0
37246	Diguanylate cyclase with PAS sensory domain	1	EC		-	-	0.0
75582	Uncharacterized protein	1			-	-	0.0
7556	Putative uncharacterized protein	1			-	-	0.0