CATH Superfamily 3.30.420.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
27562	Exodeoxyribonuclease X	29672		3D	4fzyA00	-	34.6
46005	Transposase orfB, IS3 family	18997	EC		-	-	86.2
45936	Crossover junction endodeoxyribonuclease RuvC	14605	EC	3D	1hjrA00	-	96.7
45736	Putative ribonuclease HII	14181	EC	3D	2etjA00	-	94.0
45887	Ribonuclease H, putative AFU_orthologue AFUA_1G07180	12132	EC	3D	1jl2A00	-	94.6
45238	DNA polymerase III subunit epsilon	9288	EC	3D	1j53A00	-	86.9
45678	Probable oligoribonuclease, mitochondrial	7591	EC	3D	1ytaA00	-	71.6
45932	Argonaute 2, isoform E	6906	EC	3D	4f3tA04	-	78.2
45748	Ribonuclease D	6787	EC	3D	1yt3A01	-	93.8
45256	CCR4-NOT transcription complex subunit 7	6184	EC	3D	2d5rA00	-	86.4
45925	Ribonuclease H2 subunit A	6179	EC	3D	3pufA01	-	95.8
45844	DNA polymerase III PolC-type	5124	EC	3D	2p1jA01	-	99.2
45159	Ribonuclease T	5058		3D	2is3A00	-	97.8
45903	DNA polymerase I PolA	4489	EC	3D	1d8yA01	-	93.9
45870	Ribonuclease HII	4467	EC		-	-	88.9
28922	Integrase core domain protein	4394			-	-	64.9
44904	Exodeoxyribonuclease I	3494	EC	3D	1fxxA01	-	93.9
15200	Sporulation inhibitor KapD	3034	EC		-	-	10.6
45776	DNA polymerase catalytic subunit	2856	EC	3D	3iayA03	-	85.5
44523	DNA polymerase II	2580	EC	3D	1q8iA03	-	72.0
45836	Insertion element IS1655 transposase	2538			-	-	86.9
45603	RNA exonuclease 4	1992	EC	3D	1wljA00	-	89.8
27380	Transposase for IS431mec	1229			-	-	79.5
45985	Pol polyprotein	1185	EC	3D	3hyfA00	-	98.7
44795	Polymerase DNA directed	1176	EC		-	-	89.4
33889	Ribonuclease HI	1043	EC		-	-	3.5
45725	POL polyprotein	1018	EC	3D	1ex4A01	-	96.0
45375	PAB-dependent poly A	1005	EC		-	-	89.3
45906	Probable ATP-dependent helicase DinG homolog	992	EC		-	-	76.6
1968	Transposon Tn7 transposition protein tnsB	919			-	-	71.6
45861	DNA polymerase alpha catalytic subunit	895	EC	3D	4b08A03	-	86.3
21000	IS3 family transposase orfB	857			-	-	87.6
45842	Putative gag-pro-pol polyprotein	727	EC	3D	2hb5A00	-	97.2
45955	Werner syndrome ATP-dependent helicase	667	EC	3D	2fbtA00	-	94.7
45780	DNA polymerase zeta catalytic subunit	630	EC		-	-	89.6
45766	Ribonuclease HII	623	EC		-	-	90.8
45737	RNA exonuclease 1 homolog	514	EC		-	-	91.6
45869	Putative gag-pro-pol polyprotein	466	EC		-	-	91.5
45852	ERI1 exoribonuclease 2	451		3D	3cg7A01	-	96.0
45782	Probable Pol polyprotein	418	EC	3D	5cz1A00	-	95.1
5110	Exonuclease A	401	EC		-	-	1.3
44515	Ribonuclease HII	364	EC		-	-	68.3
45072	DNA polymerase I	364	EC		-	-	67.6
45790	Ribonuclease HII	290	EC		-	-	91.4
45984	14.7 kDa ribonuclease H-like protein	274	EC	3D	3hstB00	-	81.1
45032	DNA polymerase I PolA	232	EC		-	-	68.1
45886	DNA polymerase PolB subunit 1	208	EC	3D	1wn7A02	-	92.7
46020	Transposon Tn7-like transposase protein B	185			-	-	71.4
5331	3'-5' exoribonuclease 1	177		3D	1w0hA00	-	75.0
45519	Epithelial-splicing regulatory protein 1	176			-	-	89.9
45923	RNA exonuclease 3	170			-	-	87.9
2229	Piwi-like protein 2	168	EC		-	-	83.4
45940	ISRme9 transposase ORFA protein	161			-	-	84.8
20953	K7_Rnh1p	141	EC		-	-	10.9
45967	Uncharacterized nucleolar protein C2C4.08	137			-	-	89.8
44434	DNA polymerase alpha catalytic subunit	137	EC	3D	4q5vA03	-	71.3
45119	Pro-Pol polyprotein	132	EC	3D	2x6nA00	-	78.9
45052	Transposon Ty2-OR2 Gag-Pol polyprotein	126	EC		-	-	51.9
14792	Ribonuclease D	118	EC		-	-	28.6
45751	Pol polyprotein	112	EC	3D	3hpgA02	-	89.0
46015	Cruciform cutting endonuclease 1, mitochondrial	111			-	-	87.2
45541	Three-prime repair exonuclease 1	110	EC	3D	2iocA01	-	70.8
44738	Putative RNA exonuclease NEF-sp	106			-	-	71.0
45893	Truncated Pr160 gag-pol polyprotein	98	EC	3D	1a5vA00	-	83.4
14836	PUTATIVE TRANSPOSASE [SECOND PART]	92			-	-	17.9
45091	Transcription elongation factor, mitochondrial	91			-	-	89.7
45956	DNA polymerase I, thermostable	88	EC	3D	1bgxT03	-	69.9
18494	3'-5' exonuclease family protein, ribonuclease D	86	EC		-	-	8.6
44626	DNA polymerase III subunit epsilon	85	EC		-	-	26.7
119	CCR4-NOT transcriptional complex subunit	72	EC	3D	1uocA00	-	6.3
17921	Protein NYNRIN	66			-	-	50.2
44977	NYN domain and retroviral integrase containing	65			-	-	46.2
26798	Rnh70p	58			-	-	8.2
15816	3'-5' exonuclease KapD	58			-	-	4.7
30022	Epithelial splicing regulatory protein 2	58			-	-	59.5
45688	DNA polymerase 1	58	EC	3D	1s5jA02	-	73.2
3534	DNA polymerase	56	EC		-	-	9.9
45461	DNA polymerase	53	EC		-	-	70.3
8265	Integrase core domain protein	51			-	-	68.8
22438	Probable ribonuclease H protein	50	EC		-	-	8.4
11248	ISPsy4, transposase	49			-	-	0.0
15345	DNA polymerase I	45	EC		-	-	3.4
45004	Exonuclease 3'-5' domain-containing protein 1	43			-	-	53.8
46039	Retrovirus-related Pol polyprotein from transposon gypsy	42	EC	3D	1zbfA00	-	88.9
12621	DNA polymerase III epsilon subunit	42	EC		-	-	4.1
5113	Transposon Tf2-12 polyprotein	40			-	-	2.8
27186	Uncharacterized protein	39	EC		-	-	2.2
10119	Transposase for insertion sequence element IS21	38			-	-	60.2
18298	DNA-directed DNA polymerase III epsilon subunit	37	EC		-	-	2.0
15346	DNA polymerase III epsilon subunit	36	EC		-	-	7.3
45958	DNA polymerase	34	EC	3D	1xhxA01	-	72.6
1334	DNA polymerase	32	EC		-	-	9.1
2071	DNA polymerase	31	EC		-	-	7.8
4394	DNA polymerase epsilon, catalytic subunit a, putative	31	EC		-	-	10.9
45973	Exonuclease mut-7 homolog	31			-	-	92.8
358	DNA polymerase alpha catalytic subunit	29	EC		-	-	78.9
31624	Integrase catalytic region	28			-	-	61.3
44792	Ribonuclease HII	27	EC		-	-	36.4
42184	Integrase core domain protein	26			-	-	67.7
758	DNA polymerase	25	EC		-	-	11.1
2243	DNA polymerase beta	22	EC		-	-	6.4
45952	Ribonuclease HII	22	EC		-	-	80.2
46060	Uncharacterized protein At5g06450	19		3D	1vk0A00	-	30.2
16371	Transposase for insertion sequence IS1202	19			-	-	19.4
9055	DNA polymerase	19	EC		-	-	22.1
27207	Crossover junction endodeoxyribonuclease RuvC	18	EC		-	-	54.3
44851	Pro-Pol polyprotein	18	EC	3D	2lsnA00	-	47.0
17895	Integrase catalytic region	17			-	-	34.6
8040	Transposase for insertion sequence element IS232	16			-	-	62.9
16486	Putative integrase ORF3	16			-	-	48.7
1888	DNA polymerase	16	EC		-	-	9.0
7190	Egalitarian, isoform B	16			-	-	16.9
45240	Small RNA degrading nuclease 3	15			-	-	52.7
6666	Ribonuclease HII	13	EC		-	-	19.6
23117	Retrovirus-related Pol polyprotein from transposon TNT 1-94	12	EC		-	-	53.4
4675	Polysaccharide biosynthesis protein WlaX	11			-	-	12.0
46071	Piwi protein AF_1318	11		3D	1w9hA02	-	5.6
44723	Transposase for insertion sequence element IS21-like	11			-	-	24.3
21394	Transposon Ty4-J Gag-Pol polyprotein	10	EC		-	-	32.3
45381	Probable Pol polyprotein	10	EC		-	-	45.0
27864	Ribonuclease HI	10	EC		-	-	11.4
25351	Crossover junction endodeoxyribonuclease RuvC	10	EC		-	-	11.8
80	CCR4-NOT transcription complex subunit 7/8	9	EC		-	-	4.3
44400	DNA polymerase	9	EC		-	-	22.8
44822	Ribonuclease HII	9	EC		-	-	46.9
1337	DDE-recombinase A	9		3D	1bcmA01	-	3.7
10083	Transposon Ty3-I Gag-Pol polyprotein	8	EC		-	-	25.8
34777	Truncated Pr160 gag-pol polyprotein	8	EC		-	-	13.0
4015	DNA polymerase I family protein	7	EC		-	-	15.0
45865	APSE-2 prophage DNA polymerase	7	EC		-	-	13.4
45858	Polynucleotidyl transferase, ribonuclease H-like superfamily protein	7	EC		-	-	49.8
867	DNA polymerase I A, chloroplastic/mitochondrial	6	EC		-	-	14.0
859	DNA polymerase alpha catalytic subunit	6	EC		-	-	13.5
5636	Uncharacterized exonuclease domain-containing protein At3g15140	6			-	-	8.5
24926	Putative RNA exonuclease pqe-1	6			-	-	0.0
22203	Retrovirus-related Pol polyprotein from transposon gypsy	6	EC		-	-	13.2
89	Uncharacterized protein	5			-	-	1.6
44442	Ribonuclease HII	5	EC		-	-	13.4
45416	Probable CCR4-associated factor 1 homolog 5	5	EC		-	-	54.5
31178	Integrase core domain protein	5			-	-	26.9
46042	Probable DNA polymerase	5	EC		-	-	45.7
35338	Pol polyprotein	5	EC		-	-	8.6
26059	Uncharacterized protein	4	EC		-	-	0.0
45848	Bifunctional palmitylprotein-Holliday junction e ndonuclease	4			-	-	0.0
42810	Uncharacterized transposase-like protein HI_0493	4			-	-	0.0
34911	Integrase	4			-	-	0.0
31766	Transposon Ty4-H Gag-Pol polyprotein	4	EC		-	-	0.0
8234	Putative ATP-dependent DNA helicase	4			-	-	0.0
44373	Ribonuclease HII	3	EC		-	-	13.5
35589	Pol polyprotein	3	EC		-	-	1.9
17922	Integrase	3	EC		-	-	12.6
14239	Werner Syndrome-like exonuclease	3			-	-	7.7
45123	Ribonuclease HII	3	EC		-	-	35.5
44532	Ribonuclease HII	2	EC		-	-	16.6
913	Germ cell-expressed protein R06C7.1	2			-	-	0.0
44991	Retrovirus-related Pol polyprotein from transposon 297	2	EC		-	-	16.3
1545	Probable CCR4-associated factor 1 homolog 1	2	EC		-	-	3.1
28817	Putative integrase ORF3	2			-	-	3.3
1209	Mu-like prophage FluMu transposase A	2			-	-	0.5
21907	ISHne2, transposase	2			-	-	0.0
6967	3'-5' exonuclease eri-1	2			-	-	0.0
34856	Retrovirus-related Pol polyprotein from transposon TNT 1-94	2	EC		-	-	19.3
17345	Putative transposase for insertion sequence element IS5376	2			-	-	2.7
5000	DNA polymerase 3	2	EC		-	-	1.6
15288	Retrovirus-related Pol polyprotein from transposon opus	2	EC		-	-	0.6
10075	Ribonuclease HII	1	EC		-	-	0.0
8214	Uncharacterized protein	1			-	-	0.0
4272	Uncharacterized protein L533	1			-	-	0.0
16302	DNA polymerase I domain protein	1	EC		-	-	0.0
14562	DNA polymerase	1	EC		-	-	0.0
17918	DNA polymerase III PolC-type	1	EC		-	-	0.0
17920	RNA exonuclease 4	1			-	-	0.0
32378	Copia protein	1			-	-	0.0
5195	DNA polymerase	1			-	-	0.0
24952	Pro-Pol polyprotein	1	EC		-	-	0.0
29921	Gag-Pol polyprotein	1	EC		-	-	0.0
17977	Putative exonuclease	1			-	-	0.0
12057	GM25985	1			-	-	0.0
40048	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1	1	EC		-	-	0.0
44642	DNA polymerase I	1	EC		-	-	0.0
6971	Gag-Pol polyprotein	1	EC		-	-	0.0
24958	Crossover junction endodeoxyribonuclease RuvC	1	EC		-	-	0.0
16786	Uncharacterized exonuclease CP81	1			-	-	0.0
9054	Copia protein	1			-	-	0.0
11234	Exonuclease DPD1, chloroplastic/mitochondrial	1			-	-	0.0
26808	DNA polymerase I	1	EC		-	-	0.0
7137	Gp31	1			-	-	0.0
5389	Exonuclease 3'-5' domain-containing protein 1	1			-	-	0.0
25814	Crossover junction endodeoxyribonuclease RuvC	1	EC		-	-	0.0
24545	DNA-directed DNA polymerase	1	EC		-	-	0.0
24549	RNA exonuclease 3	1			-	-	0.0