The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Dihydrodipicolinate Reductase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24349: GDH/6PGL endoplasmic bifunctional protein

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glucose-6-phosphate dehydrogenase (NADP(+)). [EC: 1.1.1.49]
D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH.
  • The enzyme catalyzes a step of the pentose phosphate pathway.
  • The enzyme is specific for NADP(+), cf. EC 1.1.1.363 and EC 1.1.1.388.
265 A0A024BXQ2 A0A024C0Q6 A0A060PSC1 A0A083YFS1 A0A086RPS7 A0A0B2DTF6 A0A0B2DXG3 A0A0B2E813 A0A0B2EAZ3 A0A0B2EIT7
(255 more...)
6-phosphogluconolactonase. [EC: 3.1.1.31]
6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate.
    3 O95479 P56201 Q8CFX1
    Glucose 1-dehydrogenase (NAD(P)(+)). [EC: 1.1.1.47]
    D-glucose + NAD(P)(+) = D-glucono-1,5-lactone + NAD(P)H.
    • This enzyme has similar activity with either NAD(+) or NADP(+).
    • Cf. EC 1.1.1.118 and EC 1.1.1.119.
    3 O95479 P56201 Q8CFX1
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