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CATH Superfamily 3.30.360.10

Dihydrodipicolinate Reductase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Dihydrodipicolinate Reductase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23675: Bifunctional aspartokinase/homoserine dehydrogenas...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Homoserine dehydrogenase. [EC: 1.1.1.3]
L-homoserine + NAD(P)(+) = L-aspartate 4-semialdehyde + NAD(P)H.
  • The enzyme from Saccharomyces cerevisiae acts most rapidly with NAD(+); the Neurospora enzyme with NADP(+).
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 2.7.2.4.
 645 A0A014NRE5 A0A017I4G2 A0A023V610 A0A023Z660 A0A024KLN7 A0A025C276 A0A026RX20 A0A026US55 A0A027TH26 A0A027Z5F8
(635 more...)
Aspartate kinase. [EC: 2.7.2.4]
ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3.
  • This is also the case for two of the four isoenzymes in Arabidopsis thaliana.
  • The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.
 553 A0A014NRE5 A0A017I4G2 A0A022PJD7 A0A023V610 A0A023Z660 A0A024KLN7 A0A025C276 A0A026RX20 A0A026US55 A0A027TH26
(543 more...)
L-arabinitol 2-dehydrogenase. [EC: 1.1.1.13]
L-arabinitol + NAD(+) = L-ribulose + NADH.
    		 130 A0A017I4G2 A0A024KLN7 A0A029K1C3 A0A069XMC6 A0A070DQA2 A0A070FJI1 A0A070SPV5 A0A070ULP6 A0A073FND6 A0A073G5L7
    (120 more...)
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