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CATH Superfamily 3.30.360.10

Dihydrodipicolinate Reductase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Dihydrodipicolinate Reductase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23400: Oxidoreductase, Gfo/Idh/MocA family

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming). [EC: 1.1.1.292]
1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.
  • Present in some but not all Rhizobium species.
  • Differs from hepatic 1,5-anhydro-D-fructose reductase, which yields 1,5-anhydro-D-glucitol as the product (see EC 1.1.1.263).
  • In Sinorhizobium morelense, the product of the reaction, 1,5-anhydro- D-mannitol, can be further metabolized to D-mannose.
  • Also reduces 1,5-anhydro-D-erythro-hexo-2,3-diulose and 2-ketoaldoses (called osones), such as D-glucosone (D-arabino-hexos-2-ulose) and 6-deoxy-D-glucosone.
  • Does not reduce common aldoses and ketoses, or non-sugar aldehydes and ketones.
 69 A0A029LEA9 A0A061KL84 A0A062WQR9 A0A064C3N0 A0A0B7L9T5 A0A0E2PNL5 A0A0E9GT57 A0A0F2DUA0 A0A0H3MSY9 A0A0I6SWN1
(59 more...)
Glucose-fructose oxidoreductase. [EC: 1.1.99.28]
D-glucose + D-fructose = D-gluconolactone + D-glucitol.
  • D-mannose, D-xylose, D-galactose, 2-deoxy-D-glucose and L-arabinose will function as aldose substrates, but with low affinities.
  • The ketose substrate must be in the open-chain form.
  • The apparent affinity for fructose is low, because little of the fructose substrate is in the open-chain form.
  • Xylulose and glycerone (dihydroxyacetone) will replace fructose, but they are poor substrates.
  • The enzyme from Zymomonas mobilis contains tightly bound NADP(+).
 12 A0A0T8QAN6 A0A0T8TLY1 A0A0U5PNF0 A0A0X9VF40 A0A123SHM1 A0A174FB63 A0A174FNY2 A0A1C5Y4S4 A0A1C7G562 A7B558
(2 more...)
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