The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 8571: Receptor-type tyrosine-protein phosphatase C
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
2 | Q6ED60 (/ISS) Q6ED61 (/ISS) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
2 | Q6ED60 (/ISS) Q6ED61 (/ISS) |
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
1 | P08575 (/IDA) |
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
1 | P08575 (/TAS) |
Transmembrane receptor protein tyrosine phosphatase activity GO:0005001
Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
1 | P08575 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P08575 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | P08575 (/IPI) |
There are 29 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of T cell mediated cytotoxicity GO:0001915
Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Negative regulation of cytokine-mediated signaling pathway GO:0001960
Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
B cell proliferation GO:0042100
The expansion of a B cell population by cell division. Follows B cell activation.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
B cell receptor signaling pathway GO:0050853
A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Positive regulation of antigen receptor-mediated signaling pathway GO:0050857
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Release of sequestered calcium ion into cytosol GO:0051209
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
2 | Q6ED60 (/ISS) Q6ED61 (/ISS) |
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
|
1 | P08575 (/IMP) |
Immunoglobulin biosynthetic process GO:0002378
The chemical reactions and pathways resulting in the formation of immunoglobulin.
|
1 | P08575 (/IMP) |
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
|
1 | P08575 (/IDA) |
Negative regulation of cell adhesion involved in substrate-bound cell migration GO:0006933
The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.
|
1 | P08575 (/IMP) |
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
1 | P08575 (/TAS) |
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
|
1 | P08575 (/IMP) |
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
|
1 | P08575 (/TAS) |
Cell cycle phase transition GO:0044770
The cell cycle process by which a cell commits to entering the next cell cycle phase.
|
1 | P08575 (/IMP) |
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
1 | P08575 (/NAS) |
Bone marrow development GO:0048539
The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.
|
1 | P08575 (/IMP) |
Stem cell development GO:0048864
The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.
|
1 | P08575 (/IMP) |
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
1 | P08575 (/IDA) |
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
1 | P08575 (/TAS) |
Positive regulation of hematopoietic stem cell migration GO:2000473
Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.
|
1 | P08575 (/IMP) |
Positive regulation of stem cell proliferation GO:2000648
Any process that activates or increases the frequency, rate or extent of stem cell proliferation.
|
1 | P08575 (/IMP) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
3 | P08575 (/ISS) Q6ED60 (/ISS) Q6ED61 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P08575 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P08575 (/TAS) |
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | P08575 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P08575 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P08575 (/IDA) |
Secretory granule membrane GO:0030667
The lipid bilayer surrounding a secretory granule.
|
1 | P08575 (/TAS) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P08575 (/IDA) |