The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 25164: Interleukin-1 receptor type 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Interleukin-1 receptor activity GO:0004908
Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.
|
1 | P27931 (/IPI) |
|
Interleukin-1 binding GO:0019966
Interacting selectively and non-covalently with interleukin-1.
|
1 | P27931 (/IPI) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of protein processing GO:0010955
Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
|
1 | P27931 (/IMP) |
|
Negative regulation of interleukin-1 alpha secretion GO:0050712
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.
|
1 | P27931 (/IMP) |
|
Negative regulation of cytokine production involved in inflammatory response GO:1900016
Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
|
1 | P27931 (/IMP) |
|
Negative regulation of interleukin-1-mediated signaling pathway GO:2000660
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.
|
1 | P27931 (/IPI) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P27931 (/IDA) |
