The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21562: SLAM family member 5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of lipopolysaccharide-mediated signaling pathway GO:0031664
Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
1 Q18PI6 (/IDA)
Negative regulation of granulocyte macrophage colony-stimulating factor production GO:0032685
Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
1 Q18PI6 (/ISO)
Negative regulation of interleukin-18 production GO:0032701
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.
1 Q18PI6 (/ISO)
Negative regulation of mast cell activation GO:0033004
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.
1 Q18PI6 (/ISO)
Regulation of macrophage activation GO:0043030
Any process that modulates the frequency or rate of macrophage activation.
1 Q18PI6 (/IDA)
Negative regulation of mast cell degranulation GO:0043305
Any process that stops, prevents, or reduces the rate of mast cell degranulation.
1 Q18PI6 (/ISO)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
1 Q18PI6 (/IDA)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
1 Q18PI6 (/IDA)
Positive regulation of monocyte chemotactic protein-1 production GO:0071639
Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.
1 Q18PI6 (/IDA)
Negative regulation of interleukin-6 secretion GO:1900165
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-6 secretion.
1 Q18PI6 (/IDA)
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
1 Q18PI6 (/IDA)
Negative regulation of interleukin-10 secretion GO:2001180
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-10 secretion.
1 Q18PI6 (/IDA)
Regulation of store-operated calcium entry GO:2001256
Any process that modulates the frequency, rate or extent of store-operated calcium entry.
1 Q18PI6 (/ISO)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q18PI6 (/ISO)
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