The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 137420: TAP binding protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q99JC6 (/IPI) Q9R233 (/IPI) |
|
TAP1 binding GO:0046978
Interacting selectively and non-covalently with the TAP1 subunit of TAP (transporter associated with antigen processing) protein.
|
1 | Q9R233 (/ISO) |
|
TAP2 binding GO:0046979
Interacting selectively and non-covalently with the TAP2 subunit of TAP (transporter associated with antigen processing) protein.
|
1 | Q9R233 (/ISO) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
1 | Q99JC6 (/NAS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MHC class I protein complex assembly GO:0002397
The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.
|
1 | Q99JC6 (/IEP) |
|
Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
|
1 | Q9R233 (/IDA) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
1 | Q9R233 (/IMP) |
|
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q9R233 (/ISO) |
|
Peptide antigen stabilization GO:0050823
Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.
|
1 | Q9R233 (/IMP) |
|
Regulation of protein complex stability GO:0061635
Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.
|
1 | Q9R233 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
|
1 | Q9R233 (/ISO) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q9R233 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9R233 (/TAS) |
|
Phagocytic vesicle membrane GO:0030670
The lipid bilayer surrounding a phagocytic vesicle.
|
1 | Q9R233 (/TAS) |
|
MHC class I peptide loading complex GO:0042824
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.
|
1 | Q99JC6 (/IDA) |
