The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 137234: Calmodulin-binding transcription activator 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
8 | A0A0B4LF06 (/IDA) A0A0B4LF15 (/IDA) A0SQK5 (/IDA) A1Z7V0 (/IDA) B7YZS4 (/IDA) B7YZU4 (/IDA) B7YZU5 (/IDA) E1JH18 (/IDA) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
8 | A0A0B4LF06 (/ISS) A0A0B4LF15 (/ISS) A0SQK5 (/ISS) A1Z7V0 (/ISS) B7YZS4 (/ISS) B7YZU4 (/ISS) B7YZU5 (/ISS) E1JH18 (/ISS) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
8 | A0A0B4LF06 (/ISS) A0A0B4LF15 (/ISS) A0SQK5 (/ISS) A1Z7V0 (/ISS) B7YZS4 (/ISS) B7YZU4 (/ISS) B7YZU5 (/ISS) E1JH18 (/ISS) |
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
8 | A0A0B4LF06 (/ISS) A0A0B4LF15 (/ISS) A0SQK5 (/ISS) A1Z7V0 (/ISS) B7YZS4 (/ISS) B7YZU4 (/ISS) B7YZU5 (/ISS) E1JH18 (/ISS) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
8 | A0A0B4LF06 (/IPI) A0A0B4LF15 (/IPI) A0SQK5 (/IPI) A1Z7V0 (/IPI) B7YZS4 (/IPI) B7YZU4 (/IPI) B7YZU5 (/IPI) E1JH18 (/IPI) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | A2A891 (/IDA) Q80Y50 (/IDA) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | O94983 (/IDA) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q80Y50 (/ISO) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | Q6NPP4 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O94983 (/IPI) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | O94983 (/IGI) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | Q80Y50 (/ISO) |
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
1 | O94983 (/IDA) |
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
1 | Q80Y50 (/ISO) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q6NPP4 (/IPI) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
8 | A0A0B4LF06 (/IMP) A0A0B4LF15 (/IMP) A0SQK5 (/IMP) A1Z7V0 (/IMP) B7YZS4 (/IMP) B7YZU4 (/IMP) B7YZU5 (/IMP) E1JH18 (/IMP) |
Deactivation of rhodopsin mediated signaling GO:0016059
The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).
|
8 | A0A0B4LF06 (/IMP) A0A0B4LF15 (/IMP) A0SQK5 (/IMP) A1Z7V0 (/IMP) B7YZS4 (/IMP) B7YZU4 (/IMP) B7YZU5 (/IMP) E1JH18 (/IMP) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | A0A0B4LF06 (/ISS) A0A0B4LF15 (/ISS) A0SQK5 (/ISS) A1Z7V0 (/ISS) B7YZS4 (/ISS) B7YZU4 (/ISS) B7YZU5 (/ISS) E1JH18 (/ISS) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
8 | A0A0B4LF06 (/IDA) A0A0B4LF15 (/IDA) A0SQK5 (/IDA) A1Z7V0 (/IDA) B7YZS4 (/IDA) B7YZU4 (/IDA) B7YZU5 (/IDA) E1JH18 (/IDA) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
6 | F4KCL4 (/TAS) O23463 (/TAS) Q6NPP4 (/TAS) Q8GSA7 (/TAS) Q9FYG2 (/TAS) Q9LSP8 (/TAS) |
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
3 | F4KCL4 (/IMP) Q6NPP4 (/IMP) Q8GSA7 (/IMP) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O94983 (/IDA) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q80Y50 (/ISO) |
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
|
1 | Q8GSA7 (/IMP) |
Cardiac muscle hypertrophy in response to stress GO:0014898
The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.
|
1 | O94983 (/IDA) |
Cardiac muscle hypertrophy in response to stress GO:0014898
The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.
|
1 | Q80Y50 (/ISO) |
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | Q8GSA7 (/IGI) |
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | Q8GSA7 (/IMP) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | F4KCL4 (/IDA) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q6NPP4 (/IMP) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O94983 (/IGI) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q80Y50 (/ISO) |
Response to freezing GO:0050826
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.
|
1 | F4KCL4 (/IMP) |
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
1 | Q8GSA7 (/IGI) |
Neuromuscular process controlling balance GO:0050885
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
|
1 | A2A891 (/IMP) |
Cellular response to aluminum ion GO:0071275
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.
|
1 | Q6NPP4 (/IEP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | A0A0B4LF06 (/IDA) A0A0B4LF15 (/IDA) A0SQK5 (/IDA) A1Z7V0 (/IDA) B7YZS4 (/IDA) B7YZU4 (/IDA) B7YZU5 (/IDA) E1JH18 (/IDA) O94983 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | A0A0B4LF06 (/ISS) A0A0B4LF15 (/ISS) A0SQK5 (/ISS) A1Z7V0 (/ISS) B7YZS4 (/ISS) B7YZU4 (/ISS) B7YZU5 (/ISS) E1JH18 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9FYG2 (/IDA) Q9Y6Y1 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q80Y50 (/ISO) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9Y6Y1 (/IDA) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | A2A891 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | A2A891 (/ISO) |