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CATH Superfamily 2.60.120.200

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25008: Alginate lyase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Mannuronate-specific alginate lyase. [EC: 4.2.2.3]
Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy- alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end.
  • The enzyme catalyzes the degradation of alginate by a beta- elimination reaction.
  • It cleaves the (1->4) bond between beta-D-mannuronate and either alpha-L-guluronate or beta-D-mannuronate, generating oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non- reducing ends and beta-D-mannuronate at the reducing end.
  • Depending on the composition of the substrate, the enzyme produces oligosaccharides ranging from two to four residues, with preference for shorter products.
  • Cf. EC 4.2.2.11.
  • Formerly EC 4.2.99.4.
 10 A0A0A1HX41 A0A0B7DFE2 A0A0R3C285 A0A0S4HW35 A0A109LJP2 A0A1K1TEH0 G8Q2I2 I4K2T4 K9NSJ5 Q59478
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