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CATH Superfamily 2.40.30.10

Translation factors

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Translation factors
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 38277: NADH-cytochrome b5 reductase 2

There are 7 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cytochrome-b5 reductase. [EC: 1.6.2.2]
NADH + 2 ferricytochrome b5 = NAD(+) + H(+) + 2 ferrocytochrome b5.
    		 4490 A0A010QHA5 A0A010QHA5 A0A010RA17 A0A010RA17 A0A010S3T3 A0A010S3T3 A0A014N2T7 A0A014N2T7 A0A015J2M1 A0A015J2M1
    (4480 more...)
    Nitrate reductase (NADH). [EC: 1.7.1.1]
    Nitrite + NAD(+) + H(2)O = nitrate + NADH.
    • Formerly EC 1.6.6.1.
    		 78 A0A0A0QLW7 A0A0A0QLW7 A0A125YVC5 A0A125YVC5 A0A167UI63 A0A167UI63 A0A178WBR8 A0A178WBR8 A2Q7D3 A2Q7D3
    (68 more...)
    Nitrate reductase (NADPH). [EC: 1.7.1.3]
    Nitrite + NADP(+) + H(2)O = nitrate + NADPH.
    • Formerly EC 1.6.6.3.
    		 24 A0A084FV35 A0A084FV35 M5C8G3 M5C8G3 P08619 P08619 P22945 P22945 P36842 P36842
    (14 more...)
    Nitrate reductase (NAD(P)H). [EC: 1.7.1.2]
    Nitrite + NAD(P)(+) + H(2)O = nitrate + NAD(P)H.
    • Formerly EC 1.6.6.2.
    		 18 A0A060T1U8 A0A060T1U8 A0A167UI63 A0A167UI63 A2QPB9 A2QPB9 A2QPC0 A2QPC0 B3WFS6 B3WFS6
    (8 more...)
    Transferred entry: 1.7.1.1. [EC: 1.6.6.1]
      		8 P92920 P92920 P92921 P92921 P92922 P92922 Q43265 Q43265
      Nitrite reductase (NAD(P)H). [EC: 1.7.1.4]
      Ammonia + 3 NAD(P)(+) + 2 H(2)O = nitrite + 3 NAD(P)H.
      • The enzymes from the fungi Neurospora crassa, Emericella nidulans and Candida nitratophila and the bacterium Aliivibrio fischeri can use either NADPH or NADH as electron donor.
      • Cf. EC 1.7.1.15.
      • Formerly EC 1.6.6.4.
      		 2 K8YSU6 K8YSU6
      3-hydroxyacyl-CoA dehydrogenase. [EC: 1.1.1.35]
      (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
      • Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3- hydroxyacylhydrolipoate.
      • Some enzymes act, more slowly, with NADP(+).
      • Broad specificity to acyl chain-length (cf. EC 1.1.1.211).
      		 2 A0A0L1HEK7 A0A0L1HEK7
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