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CATH Superfamily 2.40.30.10

Translation factors

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Translation factors
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Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 37902: Sulfate adenylyltransferase subunit 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sulfate adenylyltransferase. [EC: 2.7.7.4]
ATP + sulfate = diphosphate + adenylyl sulfate.
  • The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a bifunctional enzyme: ATP sulfurylase, which catalyzes the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate and the second step is catalyzed by the APS kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme bound APS and ATP.
  • This is in contrast to what is found in bacteria, yeasts, fungi and plants, where the formation of PAPS is carried out by two individual polypeptides, EC 2.7.7.4 and EC 2.7.1.25.
 6968 A0A009FN54 A0A009FN54 A0A009GDR5 A0A009GDR5 A0A009HG56 A0A009HG56 A0A009I5L2 A0A009I5L2 A0A009IPS1 A0A009IPS1
(6958 more...)
Adenylyl-sulfate kinase. [EC: 2.7.1.25]
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate.
  • The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a bifunctional enzyme: ATP sulfurylase, which catalyzes the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate and the second step is catalyzed by the APS kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme bound APS and ATP.
  • This is in contrast to what is found in bacteria, yeasts, fungi and plants, where the formation of PAPS is carried out by two individual polypeptides, EC 2.7.7.4 and EC 2.7.1.25.
 1250 A0A021X7I1 A0A021X7I1 A0A022FRT1 A0A022FRT1 A0A023NMP0 A0A023NMP0 A0A024KHR7 A0A024KHR7 A0A031I575 A0A031I575
(1240 more...)
Formylmethanofuran dehydrogenase. [EC: 1.2.99.5]
Formylmethanofuran + H(2)O + acceptor = CO(2) + methanofuran + reduced acceptor.
  • Tungstate can substitute for molybdate.
  • The enzyme catalyzes a reversible reaction in methanogenic bacteria, and is involved in methanogenesis from CO(2) as well as the oxidation of methyl-coenzyme M to CO(2).
  • Methyl viologen can act as acceptor.
  • Also oxidizes N-furfurylformamide.
 26 A0A0F6ANU5 A0A0F6ANU5 A0A0M1WCW2 A0A0M1WCW2 A0A1B3RWL6 A0A1B3RWL6 C0G3W4 C0G3W4 C0RGP6 C0RGP6
(16 more...)
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