CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 16778: Putative uncharacterized protein chico
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Insulin receptor binding GO:0005158
Interacting selectively and non-covalently with the insulin receptor.
|
5 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) Q9XTN2 (/ISS) |
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
|
5 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) Q9XTN2 (/ISS) |
Insulin receptor binding GO:0005158
Interacting selectively and non-covalently with the insulin receptor.
|
1 | Q9XTN2 (/IPI) |
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
|
1 | Q9XTN2 (/IGI) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9XTN2 (/IPI) |
SH2 domain binding GO:0042169
Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.
|
1 | Q9XTN2 (/ISS) |
Phosphatidylinositol 3-kinase binding GO:0043548
Interacting selectively and non-covalently with a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.
|
1 | Q9XTN2 (/ISS) |
There are 42 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Insulin-like growth factor receptor signaling pathway GO:0048009
The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands.
|
5 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) Q9XTN2 (/ISS) |
Vitellogenesis GO:0007296
The production of yolk. Yolk is a mixture of materials used for embryonic nutrition.
|
4 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) |
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
4 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) |
Multicellular organism aging GO:0010259
An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).
|
4 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) |
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
|
1 | Q9XTN2 (/IMP) |
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
1 | Q9XTN2 (/IMP) |
Primary spermatocyte growth GO:0007285
The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.
|
1 | Q9XTN2 (/IMP) |
Growth of a germarium-derived egg chamber GO:0007295
Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.
|
1 | Q9XTN2 (/IMP) |
Vitellogenesis GO:0007296
The production of yolk. Yolk is a mixture of materials used for embryonic nutrition.
|
1 | Q9XTN2 (/IMP) |
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
1 | Q9XTN2 (/IMP) |
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q9XTN2 (/IGI) |
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q9XTN2 (/IPI) |
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q9XTN2 (/NAS) |
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q9XTN2 (/TAS) |
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | Q9XTN2 (/IMP) |
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | Q9XTN2 (/TAS) |
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
|
1 | Q9XTN2 (/IMP) |
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
|
1 | Q9XTN2 (/NAS) |
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
|
1 | Q9XTN2 (/TAS) |
Multicellular organism aging GO:0010259
An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).
|
1 | Q9XTN2 (/IMP) |
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
|
1 | Q9XTN2 (/IMP) |
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
1 | Q9XTN2 (/NAS) |
Regulation of activin receptor signaling pathway GO:0032925
Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.
|
1 | Q9XTN2 (/IMP) |
Response to anoxia GO:0034059
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
|
1 | Q9XTN2 (/IDA) |
Regulation of tube length, open tracheal system GO:0035159
Ensuring that a tube in an open tracheal system is of the correct length.
|
1 | Q9XTN2 (/IMP) |
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
|
1 | Q9XTN2 (/IMP) |
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
|
1 | Q9XTN2 (/TAS) |
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
|
1 | Q9XTN2 (/IMP) |
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
|
1 | Q9XTN2 (/TAS) |
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
1 | Q9XTN2 (/IMP) |
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
1 | Q9XTN2 (/TAS) |
Cellular metabolic process GO:0044237
The chemical reactions and pathways by which individual cells transform chemical substances.
|
1 | Q9XTN2 (/TAS) |
Positive regulation of cell size GO:0045793
Any process that increases cell size.
|
1 | Q9XTN2 (/NAS) |
Positive regulation of cell size GO:0045793
Any process that increases cell size.
|
1 | Q9XTN2 (/TAS) |
Regulation of organ growth GO:0046620
Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
|
1 | Q9XTN2 (/IMP) |
Regulation of organ growth GO:0046620
Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
|
1 | Q9XTN2 (/NAS) |
Positive regulation of organ growth GO:0046622
Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
|
1 | Q9XTN2 (/NAS) |
Positive regulation of organ growth GO:0046622
Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
|
1 | Q9XTN2 (/TAS) |
Male germ-line stem cell asymmetric division GO:0048133
The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.
|
1 | Q9XTN2 (/IMP) |
Positive regulation of immune response GO:0050778
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | Q9XTN2 (/IMP) |
Germ-line stem-cell niche homeostasis GO:0060250
A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.
|
1 | Q9XTN2 (/IMP) |
Long-term synaptic potentiation GO:0060291
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
|
1 | Q9XTN2 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) Q9XTN2 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) Q9XTN2 (/ISS) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
5 | B3MPN6 (/ISS) B3N946 (/ISS) B4HWI2 (/ISS) B4NZ70 (/ISS) Q9XTN2 (/ISS) |