CATH Superfamily 2.170.40.20
Human immunodeficiency virus 1, Gp160, envelope glycoprotein
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Human immunodeficiency virus 1, Gp160, envelope glycoprotein
".
FunFam 34046: Envelope glycoprotein gp160
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P03375 (/IPI) P04578 (/IPI) Q9IV27 (/IPI) |
|
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P03375 (/IDA) |
|
CD4 receptor binding GO:0042609
Interacting selectively and non-covalently with a CD4, a receptor found on the surface of T cells, monocytes and macrophages.
|
1 | P03375 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P05877 (/IPI) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Virion attachment to host cell GO:0019062
The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.
|
34 |
O12164 (/ISS)
O41803 (/ISS)
O70902 (/ISS)
O89292 (/ISS)
P03375 (/ISS)
P03377 (/ISS)
P04579 (/ISS)
P04580 (/ISS)
P04581 (/ISS)
P04582 (/ISS)
(24 more) |
|
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
|
34 |
O12164 (/ISS)
O41803 (/ISS)
O70902 (/ISS)
O89292 (/ISS)
P03375 (/ISS)
P03377 (/ISS)
P04579 (/ISS)
P04580 (/ISS)
P04581 (/ISS)
P04582 (/ISS)
(24 more) |
|
Viral protein processing GO:0019082
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.
|
34 |
O12164 (/ISS)
O41803 (/ISS)
O70902 (/ISS)
O89292 (/ISS)
P03375 (/ISS)
P03377 (/ISS)
P04579 (/ISS)
P04580 (/ISS)
P04581 (/ISS)
P04582 (/ISS)
(24 more) |
|
Clathrin-dependent endocytosis of virus by host cell GO:0075512
Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.
|
34 |
O12164 (/ISS)
O41803 (/ISS)
O70902 (/ISS)
O89292 (/ISS)
P03375 (/ISS)
P03377 (/ISS)
P04579 (/ISS)
P04580 (/ISS)
P04581 (/ISS)
P04582 (/ISS)
(24 more) |
|
Stimulatory C-type lectin receptor signaling pathway GO:0002223
Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.
|
26 |
P03375 (/TAS)
P03377 (/TAS)
P04578 (/TAS)
P04579 (/TAS)
P04580 (/TAS)
P04581 (/TAS)
P04582 (/TAS)
P04583 (/TAS)
P04624 (/TAS)
P05877 (/TAS)
(16 more) |
|
Viral life cycle GO:0019058
A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.
|
1 | P04578 (/TAS) |
|
Virion attachment to host cell GO:0019062
The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.
|
1 | P04578 (/IDA) |
|
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
|
1 | P04578 (/IDA) |
|
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
|
1 | P04578 (/TAS) |
|
Virion assembly GO:0019068
A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.
|
1 | P04578 (/TAS) |
|
Viral protein processing GO:0019082
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.
|
1 | P04578 (/IDA) |
|
Viral protein processing GO:0019082
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.
|
1 | P04578 (/TAS) |
|
Entry into host cell GO:0030260
The invasion by an organism of a cell of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | P04578 (/TAS) |
|
Clathrin-dependent endocytosis of virus by host cell GO:0075512
Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.
|
1 | P04578 (/IDA) |
|
Actin filament reorganization GO:0090527
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.
|
1 | P04578 (/IDA) |
|
Positive regulation of establishment of T cell polarity GO:1903905
Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity.
|
1 | P04578 (/IDA) |
|
Positive regulation of plasma membrane raft polarization GO:1903908
Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization.
|
1 | P04578 (/IDA) |
|
Positive regulation of receptor clustering GO:1903911
Any process that activates or increases the frequency, rate or extent of receptor clustering.
|
1 | P04578 (/IDA) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Virion GO:0019012
The complete fully infectious extracellular virus particle.
|
34 |
O12164 (/ISS)
O41803 (/ISS)
O70902 (/ISS)
O89292 (/ISS)
P03375 (/ISS)
P03377 (/ISS)
P04579 (/ISS)
P04580 (/ISS)
P04581 (/ISS)
P04582 (/ISS)
(24 more) |
|
Host cell plasma membrane GO:0020002
The plasma membrane surrounding a host cell.
|
34 |
O12164 (/ISS)
O41803 (/ISS)
O70902 (/ISS)
O89292 (/ISS)
P03375 (/ISS)
P03377 (/ISS)
P04579 (/ISS)
P04580 (/ISS)
P04581 (/ISS)
P04582 (/ISS)
(24 more) |
|
Viral envelope GO:0019031
The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.
|
26 |
P03375 (/TAS)
P03377 (/TAS)
P04578 (/TAS)
P04579 (/TAS)
P04580 (/TAS)
P04581 (/TAS)
P04582 (/TAS)
P04583 (/TAS)
P04624 (/TAS)
P05877 (/TAS)
(16 more) |
|
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
|
1 | P04578 (/TAS) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | P04578 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P04578 (/TAS) |
|
Virion GO:0019012
The complete fully infectious extracellular virus particle.
|
1 | P04578 (/IDA) |
|
Host cell plasma membrane GO:0020002
The plasma membrane surrounding a host cell.
|
1 | P04578 (/IDA) |
|
Host cell perinuclear region of cytoplasm GO:0044220
The host cell cytoplasm situated near, or occurring around, the host nucleus.
|
1 | P03375 (/IDA) |
|
Host cell periphery GO:0044538
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.
|
1 | P03375 (/IDA) |
