The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Laminin
".
FunFam 46244: Integrin beta 8 (Predicted)
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | A0A0G2JVU1 (/IPI) D3ZP06 (/IPI) |
Extracellular matrix protein binding GO:1990430
Interacting selectively and non-covalently with a protein that is part of an extracellular matrix.
|
1 | P26012 (/IDA) |
Extracellular matrix protein binding GO:1990430
Interacting selectively and non-covalently with a protein that is part of an extracellular matrix.
|
1 | Q0VBD0 (/ISO) |
There are 30 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Gamete generation GO:0007276
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
3 | G5EGQ6 (/IGI) H1ZUX0 (/IGI) H1ZUX1 (/IGI) |
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Embryonic body morphogenesis GO:0010172
The process in which the anatomical structures of the embryonic soma are generated and organized.
|
3 | G5EGQ6 (/IGI) H1ZUX0 (/IGI) H1ZUX1 (/IGI) |
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Sexual reproduction GO:0019953
A reproduction process that creates a new organism by combining the genetic material of two organisms. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two different individuals (parents) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.
|
3 | G5EGQ6 (/IGI) H1ZUX0 (/IGI) H1ZUX1 (/IGI) |
Sexual reproduction GO:0019953
A reproduction process that creates a new organism by combining the genetic material of two organisms. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two different individuals (parents) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Defecation GO:0030421
The expulsion of feces from the rectum.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Post-embryonic body morphogenesis GO:0040032
The process in which the anatomical structures of the post-embryonic soma are generated and organized.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Inductive cell migration GO:0040039
Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Post-embryonic animal organ morphogenesis GO:0048563
Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
3 | G5EGQ6 (/IGI) H1ZUX0 (/IGI) H1ZUX1 (/IGI) |
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
3 | G5EGQ6 (/IMP) H1ZUX0 (/IMP) H1ZUX1 (/IMP) |
Ganglioside metabolic process GO:0001573
The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
1 | Q0VBD0 (/IMP) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
1 | P26012 (/TAS) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | G5EGQ6 (/IMP) |
Axonal fasciculation GO:0007413
The collection of axons into a bundle of rods, known as a fascicle.
|
1 | G5EGQ6 (/IMP) |
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | G5EGQ6 (/IMP) |
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | G5EGQ6 (/IMP) |
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
|
1 | G5EGQ6 (/IMP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P26012 (/IMP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q0VBD0 (/ISO) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P26012 (/IMP) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q0VBD0 (/ISO) |
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
1 | P26012 (/TAS) |
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
1 | P26012 (/IMP) |
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
1 | Q0VBD0 (/ISO) |
Pharynx development GO:0060465
The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.
|
1 | G5EGQ6 (/IMP) |
Placenta blood vessel development GO:0060674
The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.
|
1 | P26012 (/TAS) |
Basement membrane assembly involved in embryonic body morphogenesis GO:2001197
Any basement membrane assembly that is involved in embryonic body morphogenesis.
|
1 | G5EGQ6 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | G5EGQ6 (/IDA) H1ZUX0 (/IDA) H1ZUX1 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | G5EGQ6 (/IDA) H1ZUX0 (/IDA) H1ZUX1 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P26012 (/TAS) |
Integrin complex GO:0008305
A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
|
1 | P26012 (/TAS) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P26012 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q0VBD0 (/ISO) |
Integrin alphav-beta8 complex GO:0034686
An integrin complex that comprises one alphav subunit and one beta8 subunit.
|
1 | P26012 (/IDA) |
Integrin alphav-beta8 complex GO:0034686
An integrin complex that comprises one alphav subunit and one beta8 subunit.
|
1 | Q0VBD0 (/ISO) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P26012 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q0VBD0 (/ISO) |