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CATH Superfamily 1.20.59.10

Chorismate mutase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Chorismate mutase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2127: Bifunctional chorismate mutase/prephenate dehydrog...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Prephenate dehydrogenase. [EC: 1.3.1.12]
Prephenate + NAD(+) = 4-hydroxyphenylpyruvate + CO(2) + NADH.
  • This enzyme in the enteric bacteria also possesses EC 5.4.99.5 activity and converts chorismate into prephenate.
 218 A0A024KPQ9 A0A024LAY5 A0A026UEG2 A0A027ZLB4 A0A028DYD4 A0A029HPH8 A0A029IMM6 A0A029KIF8 A0A059I5B3 A0A064TBP2
(208 more...)
Chorismate mutase. [EC: 5.4.99.5]
Chorismate = prephenate.
    		 112 A0A024LAY5 A0A059I5B3 A0A068R9W0 A0A069XD49 A0A070SWZ0 A0A070UXU9 A0A074IH19 A0A089G823 A0A090P8F0 A0A090REN4
    (102 more...)
    Arogenate dehydrogenase. [EC: 1.3.1.43]
    L-arogenate + NAD(+) = L-tyrosine + NADH + CO(2).
    • Arogenate dehydrogenases may utilize NAD(+) (EC 1.3.1.43), NADP(+) (EC 1.3.1.78), or both (EC 1.3.1.79).
    • NAD(+)-specific enzymes have been reported from some bacteria and plants.
    • Some enzymes also possess the activity of EC 1.3.1.12.
    		 2 A0A1B1NAT6 A0A1L9F2U9
    Prephenate dehydrogenase (NADP(+)). [EC: 1.3.1.13]
    Prephenate + NADP(+) = 4-hydroxyphenylpyruvate + CO(2) + NADPH.
      		 1 A0A1L9F2U9
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