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CATH Superfamily 1.20.1300.10

Fumarate reductase/succinate dehydrogenase, transmembrane subunit

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Fumarate reductase/succinate dehydrogenase, transmembrane subunit
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2960: Succinate dehydrogenase subunit D

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Deleted entry. [EC: 1.3.99.1]
    		14 A0A060DNL9 A0A0F3N5M7 A0A0F6ASM6 A0A0M1WBR7 C3PMG5 C4ITA2 D5AW46 D7H019 G8AHQ6 P41086
    (4 more...)
    Succinate dehydrogenase (quinone). [EC: 1.3.5.1]
    Succinate + a quinone = fumarate + a quinol.
    • The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of many aerobic or facultative bacteria.
    • It catalyzes succinate oxidation in the citric acid cycle and transfers the electrons to quinones in the membrane, thus constituting a part of the aerobic respiratory chain (known as complex II).
    • In vivo the enzyme uses the quinone found in the organism - eukaryotic enzymes utilize ubiquinone, bacterial enzymes utilize ubiquinone or menaquinone, and archaebacterial enzymes from the Sulfolobus genus use caldariellaquinone.
    • Cf. EC 1.3.5.4.
    		 4 A1AZI6 Q59660 Q9RHE7 U4V1H6
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