The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Retinoid X Receptor
".
FunFam 5096: Estrogen receptor beta 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 166 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
31 |
O08537 (/ISS)
O13012 (/ISS)
O13186 (/ISS)
O46567 (/ISS)
O73673 (/ISS)
O93511 (/ISS)
P06537 (/ISS)
P49115 (/ISS)
P49843 (/ISS)
P49844 (/ISS)
(21 more) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
28 |
O13186 (/ISS)
O46567 (/ISS)
O73673 (/ISS)
O95718 (/ISS)
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P06536 (/ISS)
P06537 (/ISS)
(18 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
20 |
O08537 (/IPI)
O95718 (/IPI)
P04150 (/IPI)
P06401 (/IPI)
P06536 (/IPI)
P06537 (/IPI)
P08235 (/IPI)
P10275 (/IPI)
P11474 (/IPI)
P15207 (/IPI)
(10 more) |
Steroid hormone binding GO:1990239
Interacting selectively and non-covalently with a steroid hormone.
|
18 |
C6KE15 (/ISS)
O13186 (/ISS)
O46567 (/ISS)
O73673 (/ISS)
P06536 (/ISS)
P06537 (/ISS)
P07812 (/ISS)
P49115 (/ISS)
P49843 (/ISS)
P49844 (/ISS)
(8 more) |
Glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity GO:0038051
Combining with a glucocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, glucocorticoid-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain glucocorticoid response elements.
|
15 |
O13186 (/ISS)
O46567 (/ISS)
O73673 (/ISS)
P06536 (/ISS)
P06537 (/ISS)
P49115 (/ISS)
P49843 (/ISS)
P49844 (/ISS)
P59667 (/ISS)
P79269 (/ISS)
(5 more) |
Steroid hormone binding GO:1990239
Interacting selectively and non-covalently with a steroid hormone.
|
15 |
B8JJL3 (/IDA)
B8JJL4 (/IDA)
E7F7N2 (/IDA)
G1K325 (/IDA)
P04150 (/IDA)
P07812 (/IDA)
P16058 (/IDA)
P49843 (/IDA)
P57717 (/IDA)
P57782 (/IDA)
(5 more) |
Estrogen receptor activity GO:0030284
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
|
12 |
A0A060X747 (/IDA)
B8JJL3 (/IDA)
B8JJL4 (/IDA)
E7F7N2 (/IDA)
P16058 (/IDA)
P57717 (/IDA)
Q62986 (/IDA)
Q7ZU32 (/IDA)
Q90Z59 (/IDA)
Q92731 (/IDA)
(2 more) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
11 |
F1Q8K8 (/IDA)
F1QH45 (/IDA)
F6PD98 (/IDA)
O08580 (/IDA)
P04150 (/IDA)
P10275 (/IDA)
P19091 (/IDA)
Q61539 (/IDA)
Q6Q6F3 (/IDA)
Q6Q6F6 (/IDA)
(1 more) |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Androgen receptor activity GO:0004882
Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Androgen binding GO:0005497
Interacting selectively and non-covalently with any androgen, male sex hormones.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
11 |
O95718 (/IDA)
P06536 (/IDA)
P06537 (/IDA)
P11474 (/IDA)
P15207 (/IDA)
P19091 (/IDA)
P22199 (/IDA)
Q5QJV7 (/IDA)
Q61539 (/IDA)
Q62986 (/IDA)
(1 more) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding GO:0038052
Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
7 | B8JJL3 (/IDA) B8JJL4 (/IDA) E7F7N2 (/IDA) P57717 (/IDA) Q7ZU32 (/IDA) Q90Z59 (/IDA) Q92731 (/IDA) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
7 | C6KE15 (/ISS) O08580 (/ISS) P11475 (/ISS) Q5I1Z4 (/ISS) Q5QJV7 (/ISS) Q61539 (/ISS) Q6QMY5 (/ISS) |
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
6 | B0V3V6 (/IDA) P04150 (/IDA) P22199 (/IDA) Q1L686 (/IDA) Q62986 (/IDA) Q8VII8 (/IDA) |
Androgen binding GO:0005497
Interacting selectively and non-covalently with any androgen, male sex hormones.
|
6 | A4GT83 (/IDA) O93244 (/IDA) P10275 (/IDA) P16058 (/IDA) Q7T1K4 (/IDA) Q9I8F5 (/IDA) |
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
6 | P06401 (/IPI) P07812 (/IPI) P10275 (/IPI) P19091 (/IPI) Q62986 (/IPI) Q92731 (/IPI) |
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
|
5 | O08580 (/IDA) P04150 (/IDA) P06401 (/IDA) P10275 (/IDA) Q62986 (/IDA) |
Core promoter sequence-specific DNA binding GO:0001046
Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
|
5 | P49843 (/IDA) Q62986 (/IDA) Q6RKQ3 (/IDA) Q92731 (/IDA) Q9IAC6 (/IDA) |
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
5 | O08580 (/IDA) P04150 (/IDA) P06401 (/IDA) P10275 (/IDA) Q62986 (/IDA) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
5 | P06401 (/TAS) P10275 (/TAS) P11474 (/TAS) P15207 (/TAS) Q92731 (/TAS) |
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
|
5 | A4GT83 (/IDA) B0V3V6 (/IDA) Q00175 (/IDA) Q1L686 (/IDA) Q62986 (/IDA) |
Androgen receptor activity GO:0004882
Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II.
|
5 | A4GT83 (/IDA) P10275 (/IDA) P15207 (/IDA) P19091 (/IDA) Q7T1K4 (/IDA) |
Glucocorticoid receptor activity GO:0004883
Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.
|
5 | F6PEW1 (/IDA) P06537 (/IDA) P49843 (/IDA) Q1XHK0 (/IDA) Q6RKQ3 (/IDA) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
4 | P04150 (/TAS) P08235 (/TAS) P10275 (/TAS) Q92731 (/TAS) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
4 | P06536 (/IPI) P10275 (/IPI) P15207 (/IPI) Q61539 (/IPI) |
Estrogen receptor activity GO:0030284
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
|
4 | P50242 (/ISS) Q0H3B5 (/ISS) Q4ZHP9 (/ISS) Q5YFR8 (/ISS) |
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
|
4 | P22199 (/IDA) Q62986 (/IDA) Q9IAK1 (/IDA) Q9YHZ7 (/IDA) |
Estradiol binding GO:1903924
Interacting selectively and non-covalently with estradiol.
|
4 | P50242 (/ISS) Q0H3B5 (/ISS) Q4ZHP9 (/ISS) Q5YFR8 (/ISS) |
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
|
3 | P06537 (/ISO) P19091 (/ISO) Q00175 (/ISO) |
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
3 | P06537 (/ISO) P19091 (/ISO) Q00175 (/ISO) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
3 | O08537 (/IDA) O08580 (/IDA) P06537 (/IDA) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
3 | P06536 (/IDA) P10275 (/IDA) P15207 (/IDA) |
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
|
3 | P06401 (/TAS) P08235 (/TAS) Q92731 (/TAS) |
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
3 | P06401 (/IPI) P10275 (/IPI) P15207 (/IPI) |
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
3 | O08537 (/ISO) P19091 (/ISO) Q00175 (/ISO) |
Estrogen receptor activity GO:0030284
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
|
3 | P16058 (/IMP) Q62986 (/IMP) Q9YHZ7 (/IMP) |
Cortisol receptor activity GO:0031963
Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.
|
3 | P49843 (/IDA) Q6RKQ3 (/IDA) Q9IAC6 (/IDA) |
Estrogen response element binding GO:0034056
Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.
|
3 | P16058 (/IDA) Q62986 (/IDA) Q92731 (/IDA) |
Transcription factor activity, direct ligand regulated sequence-specific DNA binding GO:0098531
A DNA binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors.
|
3 | P49843 (/IDA) Q6RKQ3 (/IDA) Q9IAC6 (/IDA) |
RNA polymerase II core binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Transcriptional repressor activity, RNA polymerase II transcription factor binding GO:0001191
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
|
2 | P11475 (/ISS) Q61539 (/ISS) |
Transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding GO:0001205
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
2 | O95718 (/ISS) P11475 (/ISS) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | P10275 (/NAS) P62509 (/NAS) |
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
2 | P06536 (/IDA) P22199 (/IDA) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | P06536 (/IMP) P22199 (/IMP) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | P06537 (/ISO) P19091 (/ISO) |
Transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
|
2 | P22199 (/IMP) Q63449 (/IMP) |
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
2 | P06536 (/IDA) Q61539 (/IDA) |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
2 | P10275 (/IDA) Q9IAK1 (/IDA) |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
2 | P62509 (/NAS) Q92731 (/NAS) |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
2 | O95718 (/TAS) P11474 (/TAS) |
Glucocorticoid receptor activity GO:0004883
Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.
|
2 | C6KE15 (/ISS) Q5I1Z4 (/ISS) |
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | P19091 (/ISO) Q00175 (/ISO) |
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
2 | P22199 (/IMP) Q63449 (/IMP) |
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
2 | Q9IAK1 (/IDA) W5UDK8 (/IDA) |
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
2 | P11474 (/IPI) P15207 (/IPI) |
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
|
2 | Q62986 (/IMP) Q63449 (/IMP) |
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
|
2 | P06536 (/IPI) Q62986 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | P06536 (/IDA) P22199 (/IDA) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | P49843 (/IMP) Q61539 (/IMP) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | P06536 (/IDA) P22199 (/IDA) |
AF-2 domain binding GO:0050682
Interacting selectively and non-covalently with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.
|
2 | P62508 (/ISS) P62510 (/ISS) |
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
2 | P06401 (/IDA) P10275 (/IDA) |
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
2 | P19091 (/ISO) Q00175 (/ISO) |
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
|
2 | P04150 (/IPI) P07812 (/IPI) |
Estradiol binding GO:1903924
Interacting selectively and non-covalently with estradiol.
|
2 | A0A060X747 (/IDA) P16058 (/IDA) |
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
1 | P62509 (/IDA) |
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
|
1 | Q61539 (/IDA) |
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
|
1 | O95718 (/ISS) |
RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0000981
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | A4GT83 (/IDA) |
RNA polymerase II core binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
|
1 | Q61539 (/IDA) |
RNA polymerase II regulatory region DNA binding GO:0001012
Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | P06536 (/IDA) |
Core promoter sequence-specific DNA binding GO:0001046
Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
|
1 | O08537 (/ISO) |
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | P04150 (/IDA) |
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | Q61539 (/IMP) |
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | P06537 (/ISO) |
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O08580 (/IDA) |
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | P10275 (/IPI) |
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | P19091 (/ISO) |
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
1 | Q61539 (/IDA) |
Transcriptional repressor activity, RNA polymerase II transcription factor binding GO:0001191
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
|
1 | O95718 (/IDA) |
Transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding GO:0001205
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | Q61539 (/IDA) |
Transcription coactivator binding GO:0001223
Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | Q61539 (/IPI) |
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | P62509 (/IDA) |
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | P62509 (/IMP) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q9GLW0 (/IC) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | P16058 (/IMP) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q9IAK1 (/ISS) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | P19091 (/ISO) |
Transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
|
1 | Q61539 (/IMP) |
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | O95718 (/ISS) |
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | Q92731 (/TAS) |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
1 | Q00175 (/IMP) |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
1 | P19091 (/ISO) |
Androgen receptor activity GO:0004882
Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II.
|
1 | P10275 (/IMP) |
Androgen receptor activity GO:0004882
Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II.
|
1 | P19091 (/ISO) |
Androgen receptor activity GO:0004882
Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II.
|
1 | P10275 (/NAS) |
Androgen receptor activity GO:0004882
Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II.
|
1 | P10275 (/TAS) |
Glucocorticoid receptor activity GO:0004883
Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.
|
1 | P04150 (/TAS) |
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
1 | P06536 (/IPI) |
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
1 | P06537 (/ISO) |
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
1 | Q92731 (/TAS) |
Androgen binding GO:0005497
Interacting selectively and non-covalently with any androgen, male sex hormones.
|
1 | P15207 (/IMP) |
Androgen binding GO:0005497
Interacting selectively and non-covalently with any androgen, male sex hormones.
|
1 | P19091 (/ISO) |
Androgen binding GO:0005497
Interacting selectively and non-covalently with any androgen, male sex hormones.
|
1 | P10275 (/NAS) |
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
1 | P62509 (/NAS) |
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
1 | P10275 (/IDA) |
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
1 | P10275 (/IPI) |
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
1 | P19091 (/ISO) |
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
1 | P10275 (/TAS) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | P19091 (/ISO) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | O95718 (/ISS) |
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
|
1 | Q62986 (/IPI) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | P06536 (/TAS) |
Mineralocorticoid receptor activity GO:0017082
Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
1 | P22199 (/IDA) |
Estrogen receptor activity GO:0030284
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
|
1 | O08537 (/ISO) |
Estrogen receptor activity GO:0030284
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
|
1 | Q92731 (/TAS) |
Estrogen receptor binding GO:0030331
Interacting selectively and non-covalently with an estrogen receptor.
|
1 | P16058 (/IPI) |
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
1 | P06536 (/IDA) |
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
1 | P07812 (/IPI) |
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
|
1 | P06536 (/IPI) |
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
1 | P06536 (/IDA) |
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
|
1 | P07812 (/IDA) |
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
|
1 | P07812 (/ISS) |
SUMO binding GO:0032183
Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
|
1 | P04150 (/IPI) |
SUMO binding GO:0032183
Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
|
1 | P06537 (/ISO) |
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P06536 (/IDA) |
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P06536 (/IPI) |
Ribonucleotide binding GO:0032553
Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
|
1 | P15207 (/IDA) |
Estrogen response element binding GO:0034056
Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.
|
1 | O08537 (/ISO) |
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
1 | Q61539 (/IMP) |
Glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity GO:0038051
Combining with a glucocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, glucocorticoid-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain glucocorticoid response elements.
|
1 | P04150 (/IDA) |
Glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity GO:0038051
Combining with a glucocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, glucocorticoid-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain glucocorticoid response elements.
|
1 | P06537 (/ISO) |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding GO:0038052
Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
1 | O08537 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P16058 (/IPI) |
Peroxisome proliferator activated receptor binding GO:0042975
Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma.
|
1 | Q62986 (/IPI) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q61539 (/ISO) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | P10275 (/IDA) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | P19091 (/ISO) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | P06537 (/IDA) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | P10275 (/NAS) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | P06536 (/TAS) |
Receptor antagonist activity GO:0048019
Interacts with receptors to reduce the action of another ligand, the agonist.
|
1 | Q92731 (/NAS) |
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
1 | P15207 (/IPI) |
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
1 | Q7T1K4 (/ISS) |
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
|
1 | P06536 (/IDA) |
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
|
1 | P06537 (/ISO) |
POU domain binding GO:0070974
Interacting selectively and non-covalently with a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.
|
1 | P19091 (/IDA) |
Cortisol binding GO:1903794
Interacting selectively and non-covalently with cortisol.
|
1 | Q6RKQ3 (/IC) |
Cortisol binding GO:1903794
Interacting selectively and non-covalently with cortisol.
|
1 | Q9IAC6 (/IMP) |
Corticosterone binding GO:1903875
Interacting selectively and non-covalently with corticosterone.
|
1 | Q9IAC6 (/IMP) |
11-deoxycortisol binding GO:1903876
Interacting selectively and non-covalently with 11-deoxycortisol.
|
1 | Q9IAC6 (/IMP) |
21-deoxycortisol binding GO:1903877
Interacting selectively and non-covalently with 21-deoxycortisol.
|
1 | Q9IAC6 (/IMP) |
11-deoxycorticosterone binding GO:1903878
Interacting selectively and non-covalently with 11-deoxycorticosterone.
|
1 | Q9IAC6 (/IMP) |
11beta-hydroxyprogesterone binding GO:1903879
Interacting selectively and non-covalently with 11beta-hydroxyprogesterone.
|
1 | Q9IAC6 (/IMP) |
17alpha-hydroxyprogesterone binding GO:1903880
Interacting selectively and non-covalently with 17alpha-hydroxyprogesterone.
|
1 | Q9IAC6 (/IMP) |
Estradiol binding GO:1903924
Interacting selectively and non-covalently with estradiol.
|
1 | Q62986 (/IPI) |
Steroid hormone binding GO:1990239
Interacting selectively and non-covalently with a steroid hormone.
|
1 | Q62986 (/IPI) |
Steroid hormone binding GO:1990239
Interacting selectively and non-covalently with a steroid hormone.
|
1 | P06537 (/ISO) |
There are 349 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
27 |
O13186 (/ISS)
O46567 (/ISS)
O73673 (/ISS)
O95718 (/ISS)
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P06537 (/ISS)
P11474 (/ISS)
(17 more) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
23 |
A0A023PI52 (/ISS)
A0A087RF69 (/ISS)
A0A091F184 (/ISS)
A0A091FM40 (/ISS)
A0A091GQZ1 (/ISS)
A0A091IP29 (/ISS)
A0A091IR26 (/ISS)
A0A091K193 (/ISS)
A0A091PAL5 (/ISS)
A0A091R950 (/ISS)
(13 more) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
21 |
O08537 (/ISS)
O95718 (/ISS)
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P11475 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
(11 more) |
Cellular response to steroid hormone stimulus GO:0071383
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
14 |
O13186 (/ISS)
O46567 (/ISS)
O73673 (/ISS)
P06536 (/ISS)
P49115 (/ISS)
P49843 (/ISS)
P49844 (/ISS)
P59667 (/ISS)
P79269 (/ISS)
P79686 (/ISS)
(4 more) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Intracellular receptor signaling pathway GO:0030522
Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Positive regulation of phosphorylation GO:0042327
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Negative regulation of integrin biosynthetic process GO:0045720
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Regulation of establishment of protein localization to plasma membrane GO:0090003
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Negative regulation of extrinsic apoptotic signaling pathway GO:2001237
Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.
|
11 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
Q9GKL7 (/ISS)
(1 more) |
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
9 | O97775 (/ISS) O97776 (/ISS) O97952 (/ISS) O97960 (/ISS) P49699 (/ISS) Q6QT55 (/ISS) Q8MIK0 (/ISS) Q9GKL7 (/ISS) Q9TT90 (/ISS) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
9 | F6PEW1 (/IDA) P10275 (/IDA) P15207 (/IDA) P62509 (/IDA) Q1XHK0 (/IDA) Q61539 (/IDA) Q62986 (/IDA) Q63449 (/IDA) Q92731 (/IDA) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
9 | O08580 (/IDA) P04150 (/IDA) P06401 (/IDA) P06536 (/IDA) P10275 (/IDA) P19091 (/IDA) Q61539 (/IDA) Q62986 (/IDA) Q92731 (/IDA) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
8 | F1Q8K8 (/IDA) F1QH45 (/IDA) F6PD98 (/IDA) P04150 (/IDA) P06537 (/IDA) P10275 (/IDA) Q6Q6F3 (/IDA) Q6Q6F6 (/IDA) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | O08580 (/ISS) P11475 (/ISS) P62509 (/ISS) P62510 (/ISS) Q5QJV7 (/ISS) Q5RAM2 (/ISS) Q61539 (/ISS) Q6QMY5 (/ISS) |
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
|
8 | O95718 (/TAS) P04150 (/TAS) P06401 (/TAS) P08235 (/TAS) P10275 (/TAS) P11474 (/TAS) P62508 (/TAS) Q92731 (/TAS) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | F6PEW1 (/IDA) O95718 (/IDA) P04150 (/IDA) P06537 (/IDA) P19091 (/IDA) P62508 (/IDA) Q1XHK0 (/IDA) |
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
|
7 | B8JJL3 (/IDA) B8JJL4 (/IDA) E7F7N2 (/IDA) P07812 (/IDA) P57717 (/IDA) Q7ZU32 (/IDA) Q90Z59 (/IDA) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
5 | P04150 (/TAS) P06401 (/TAS) P08235 (/TAS) P10275 (/TAS) Q92731 (/TAS) |
Multicellular organismal response to stress GO:0033555
Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
5 | A0A0R4ICJ8 (/IEP) A6YIH7 (/IEP) F6PEW1 (/IEP) Q1L689 (/IEP) Q1XHK0 (/IEP) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | O08580 (/IMP) P06536 (/IMP) P10275 (/IMP) P19091 (/IMP) P62509 (/IMP) |
Positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
5 | O08537 (/ISS) Q62986 (/ISS) Q9TTE5 (/ISS) Q9TU15 (/ISS) Q9XSW2 (/ISS) |
Response to cortisol GO:0051414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
|
5 | F6PEW1 (/IDA) P49843 (/IDA) Q1XHK0 (/IDA) Q6RKQ3 (/IDA) Q9IAC6 (/IDA) |
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
4 | A0A060X747 (/IDA) P16058 (/IDA) P57717 (/IDA) P57782 (/IDA) |
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
4 | P50242 (/ISS) Q0H3B5 (/ISS) Q4ZHP9 (/ISS) Q5YFR8 (/ISS) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | O08537 (/ISO) P06537 (/ISO) P19091 (/ISO) Q00175 (/ISO) |
Response to cortisol GO:0051414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
|
4 | F6PEW1 (/IMP) P49843 (/IMP) Q1XHK0 (/IMP) Q6RKQ3 (/IMP) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | O08580 (/IDA) Q62986 (/IDA) Q92731 (/IDA) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | O08537 (/ISO) P06537 (/ISO) P19091 (/ISO) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | P06537 (/ISO) P62509 (/ISO) Q61539 (/ISO) |
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
|
3 | P06401 (/TAS) P10275 (/TAS) Q92731 (/TAS) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
3 | P49843 (/IDA) Q6RKQ3 (/IDA) Q9IAC6 (/IDA) |
Intracellular estrogen receptor signaling pathway GO:0030520
Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
|
3 | O08537 (/IMP) P16058 (/IMP) Q9YHZ7 (/IMP) |
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
3 | P15207 (/IEP) Q5QJV7 (/IEP) Q62986 (/IEP) |
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
|
3 | F6PEW1 (/IMP) Q1XHK0 (/IMP) Q6RKQ3 (/IMP) |
Otic vesicle development GO:0071599
The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.
|
3 | F1QH45 (/IMP) F6PD98 (/IMP) Q5RJ38 (/IMP) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P04150 (/IMP) P10275 (/IMP) |
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
|
2 | P19091 (/IMP) Q61539 (/IMP) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
2 | P06537 (/ISO) P19091 (/ISO) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P11474 (/IMP) Q00175 (/IMP) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P62509 (/NAS) Q7T1K4 (/NAS) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | P15207 (/IMP) P19091 (/IMP) |
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
2 | P11475 (/ISS) Q61539 (/ISS) |
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | P10275 (/IDA) Q63449 (/IDA) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | P10275 (/IMP) Q6RKQ3 (/IMP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | C6KE15 (/ISS) Q5I1Z4 (/ISS) |
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
|
2 | P06536 (/IEP) Q62986 (/IEP) |
Stem cell division GO:0017145
The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Regulation of metabolic process GO:0019222
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
2 | O95718 (/IDA) Q61539 (/IDA) |
Growth hormone secretion GO:0030252
The regulated release of growth hormone from secretory granules into the blood.
|
2 | A0A1D5PRD7 (/IDA) G1K325 (/IDA) |
Intracellular estrogen receptor signaling pathway GO:0030520
Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
|
2 | P16058 (/IDA) Q92731 (/IDA) |
Intracellular estrogen receptor signaling pathway GO:0030520
Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
|
2 | Q62986 (/TAS) Q92731 (/TAS) |
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
2 | P10275 (/IDA) P19091 (/IDA) |
Ovulation GO:0030728
The release of a mature ovum/oocyte from an ovary.
|
2 | B0V3V6 (/IMP) Q1L686 (/IMP) |
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | P06536 (/IEP) P15207 (/IEP) |
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
2 | P15207 (/IEP) Q62986 (/IEP) |
Light adaption GO:0036367
The ability of a photoreceptor to adjust to varying levels of light.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
2 | P06536 (/IDA) P22199 (/IDA) |
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
2 | O08537 (/IMP) Q5QJV7 (/IMP) |
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
|
2 | Q62986 (/IEP) Q63449 (/IEP) |
Cell dedifferentiation GO:0043697
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P15207 (/IDA) Q61539 (/IDA) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q5QJV7 (/IMP) Q61539 (/IMP) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | O08537 (/ISO) P19091 (/ISO) |
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
2 | C6KE15 (/ISS) Q5I1Z4 (/ISS) |
Circadian behavior GO:0048512
The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
|
2 | F6PEW1 (/IGI) Q1XHK0 (/IGI) |
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
|
2 | O08537 (/IMP) P19091 (/IMP) |
Response to cortisol GO:0051414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
|
2 | C6KE15 (/ISS) Q5I1Z4 (/ISS) |
Regulation of corticotropin secretion GO:0051459
Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.
|
2 | A0A1D5PRD7 (/IMP) G1K325 (/IMP) |
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Somatotropin secreting cell differentiation GO:0060126
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.
|
2 | A0A1D5PRD7 (/IMP) G1K325 (/IMP) |
Prostate gland epithelium morphogenesis GO:0060740
The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
|
2 | O08537 (/IMP) P19091 (/IMP) |
Tertiary branching involved in mammary gland duct morphogenesis GO:0060748
The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.
|
2 | P19091 (/IMP) Q00175 (/IMP) |
Calcium ion import GO:0070509
The directed movement of calcium ions into a cell or organelle.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Cellular response to follicle-stimulating hormone stimulus GO:0071372
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
|
2 | P15207 (/IEP) Q63449 (/IEP) |
Cellular response to corticotropin-releasing hormone stimulus GO:0071376
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.
|
2 | A0A1D5PRD7 (/IDA) G1K325 (/IDA) |
Cellular response to steroid hormone stimulus GO:0071383
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
2 | P06537 (/ISO) P19091 (/ISO) |
Cellular response to corticosterone stimulus GO:0071386
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
|
2 | A0A1D5PRD7 (/IDA) G1K325 (/IDA) |
Response to dexamethasone GO:0071548
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
|
2 | F6PEW1 (/IDA) Q1XHK0 (/IDA) |
Response to dexamethasone GO:0071548
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
|
2 | P06536 (/IEP) Q62986 (/IEP) |
Cellular response to dexamethasone stimulus GO:0071549
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
|
2 | P04150 (/IMP) P06536 (/IMP) |
Positive regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071931
Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Positive regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090282
Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Cellular response to aldosterone GO:1904045
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.
|
2 | A0A1D5PRD7 (/IDA) G1K325 (/IDA) |
Regulation of ion homeostasis GO:2000021
Any process that modulates the frequency, rate or extent of ion homeostasis.
|
2 | F6PEW1 (/IMP) Q1XHK0 (/IMP) |
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
1 | Q62986 (/IEP) |
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
1 | O08537 (/IMP) |
Ovulation from ovarian follicle GO:0001542
The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.
|
1 | Q00175 (/IMP) |
Luteinization GO:0001553
The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
|
1 | Q63449 (/IEP) |
Behavioral fear response GO:0001662
An acute behavioral change resulting from a perceived external threat.
|
1 | Q62986 (/IDA) |
Neuron migration GO:0001764
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
|
1 | O08537 (/IMP) |
Trophectodermal cellular morphogenesis GO:0001831
The morphogenesis of trophectoderm cells.
|
1 | Q61539 (/IMP) |
Trophectodermal cell proliferation GO:0001834
The proliferation of cells in the trophectoderm.
|
1 | Q61539 (/IMP) |
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
|
1 | Q61539 (/IMP) |
Epithelial cell maturation GO:0002070
The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
|
1 | Q00175 (/IMP) |
Leukocyte mediated immunity GO:0002443
Any process involved in the carrying out of an immune response by a leukocyte.
|
1 | Q689Y8 (/IMP) |
Developmental process involved in reproduction GO:0003006
A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
|
1 | Q689Y8 (/IMP) |
Regulation of systemic arterial blood pressure GO:0003073
The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
|
1 | P19091 (/IGI) |
Epithelial cell morphogenesis GO:0003382
The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.
|
1 | P19091 (/IGI) |
Regulation of gluconeogenesis GO:0006111
Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
1 | P06537 (/IMP) |
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | P06536 (/IMP) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | P10275 (/IMP) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | P04150 (/TAS) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q92731 (/TAS) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P19091 (/IMP) |
Transcription from RNA polymerase II promoter GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
1 | P04150 (/TAS) |
Transport GO:0006810
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
|
1 | P10275 (/TAS) |
Cellular sodium ion homeostasis GO:0006883
Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell.
|
1 | Q8VII8 (/IMP) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
1 | P11474 (/TAS) |
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
|
1 | P62509 (/NAS) |
Single fertilization GO:0007338
The union of male and female gametes to form a zygote.
|
1 | P19091 (/IGI) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | P06536 (/IEP) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | O08537 (/IMP) |
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
|
1 | P10275 (/NAS) |
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
1 | P06536 (/IEP) |
Excretion GO:0007588
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
|
1 | Q8VII8 (/IMP) |
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
|
1 | Q62986 (/IMP) |
Copulation GO:0007620
The act of sexual union between male and female, involving the transfer of sperm.
|
1 | P15207 (/IMP) |
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | P06536 (/IEP) |
Male courtship behavior GO:0008049
The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
|
1 | P15207 (/IMP) |
Androgen metabolic process GO:0008209
The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
|
1 | P06536 (/IEP) |
Glucocorticoid metabolic process GO:0008211
The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
|
1 | P06537 (/IMP) |
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | O95718 (/IDA) |
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | P10275 (/NAS) |
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | P19091 (/ISO) |
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | O08537 (/IGI) |
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | P10275 (/IMP) |
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | P19091 (/ISO) |
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
|
1 | Q9IAK1 (/TAS) |
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | Q62986 (/IEP) |
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | P19091 (/IGI) |
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | P19091 (/IMP) |
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
|
1 | Q62986 (/IEP) |
Hormone-mediated apoptotic signaling pathway GO:0008628
A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.
|
1 | O08537 (/IMP) |
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
|
1 | P06536 (/IEP) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | A0A1D5PRD7 (/IDA) |
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
|
1 | P57717 (/IDA) |
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
|
1 | Q9IAK1 (/TAS) |
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
|
1 | Q62986 (/IEP) |
Fertilization GO:0009566
The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
|
1 | P19091 (/IMP) |
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
|
1 | Q689Y8 (/IDA) |
Response to hormone GO:0009725
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
|
1 | Q62986 (/IEP) |
Cellular process GO:0009987
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
|
1 | P19091 (/IDA) |
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P19091 (/IMP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P19091 (/ISO) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P06401 (/IEP) |
Positive regulation of receptor biosynthetic process GO:0010870
Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | P16058 (/IMP) |
Negative regulation of receptor biosynthetic process GO:0010871
Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q6RKQ3 (/IMP) |
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
|
1 | P06536 (/IMP) |
Positive regulation of glutamate secretion GO:0014049
Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
|
1 | P06536 (/IMP) |
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | Q689Y8 (/IDA) |
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | Q62986 (/IEP) |
Skeletal muscle hypertrophy GO:0014734
The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.
|
1 | P15207 (/IMP) |
Response to inactivity GO:0014854
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.
|
1 | P06536 (/IEP) |
Muscle atrophy GO:0014889
A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
|
1 | P06536 (/IEP) |
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
|
1 | Q63449 (/IMP) |
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
|
1 | P10275 (/NAS) |
Diterpenoid metabolic process GO:0016101
The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.
|
1 | Q63449 (/IEP) |
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | P10275 (/TAS) |
Response to insecticide GO:0017085
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
|
1 | Q62986 (/IEP) |
Stem cell division GO:0017145
The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
|
1 | Q61539 (/IMP) |
Male somatic sex determination GO:0019102
The determination of sex and sexual phenotypes in a male organism's soma.
|
1 | P19091 (/IMP) |
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
1 | Q61539 (/IMP) |
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
1 | Q61539 (/ISO) |
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
1 | P11475 (/ISS) |
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
|
1 | Q62986 (/IEP) |
Limbic system development GO:0021761
The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.
|
1 | Q689Y8 (/IMP) |
Amygdala development GO:0021764
The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.
|
1 | Q62986 (/IEP) |
Hypothalamus development GO:0021854
The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.
|
1 | Q62986 (/IEP) |
Regulation of ossification GO:0030278
Any process that modulates the frequency, rate or extent of bone formation.
|
1 | Q5QJV7 (/IMP) |
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
1 | Q92731 (/NAS) |
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
|
1 | P06536 (/IEP) |
Adrenal gland development GO:0030325
The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
|
1 | P06537 (/IMP) |
Intracellular steroid hormone receptor signaling pathway GO:0030518
A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.
|
1 | Q62986 (/IDA) |
Intracellular estrogen receptor signaling pathway GO:0030520
Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
|
1 | O08537 (/ISO) |
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
1 | P15207 (/IMP) |
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
1 | P19091 (/ISO) |
Intracellular receptor signaling pathway GO:0030522
Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
|
1 | P10275 (/IDA) |
Intracellular receptor signaling pathway GO:0030522
Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
|
1 | P19091 (/ISO) |
Prostate gland development GO:0030850
The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
|
1 | Q62986 (/IEP) |
Prostate gland development GO:0030850
The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
|
1 | P10275 (/NAS) |
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
|
1 | Q00175 (/IMP) |
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
1 | Q62986 (/IEP) |
Negative regulation of synaptic plasticity GO:0031914
A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
1 | P06536 (/IMP) |
Regulation of glucocorticoid biosynthetic process GO:0031946
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
|
1 | P06537 (/IMP) |
Mineralocorticoid receptor signaling pathway GO:0031959
Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor.
|
1 | P22199 (/IMP) |
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | P16058 (/IMP) |
Otolith formation GO:0032475
The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.
|
1 | Q5RJ38 (/IMP) |
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
|
1 | P07812 (/IDA) |
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
|
1 | Q63449 (/IEP) |
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
|
1 | P07812 (/ISS) |
Negative regulation of intracellular estrogen receptor signaling pathway GO:0033147
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
|
1 | Q6RKQ3 (/IMP) |
Positive regulation of intracellular estrogen receptor signaling pathway GO:0033148
Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
|
1 | P19091 (/IMP) |
Leydig cell differentiation GO:0033327
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.
|
1 | P19091 (/IMP) |
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
1 | P16058 (/IDA) |
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
1 | Q62986 (/IMP) |
Response to genistein GO:0033595
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.
|
1 | Q62986 (/IEP) |
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
|
1 | P19091 (/IGI) |
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q62986 (/IEP) |
Paracrine signaling GO:0038001
The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.
|
1 | Q00175 (/IMP) |
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
|
1 | Q6Q6F6 (/IMP) |
Response to cocaine GO:0042220
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.
|
1 | Q63449 (/IDA) |
Positive regulation of phosphorylation GO:0042327
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
|
1 | P10275 (/IMP) |
Positive regulation of phosphorylation GO:0042327
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
|
1 | P19091 (/ISO) |
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q62986 (/IEP) |
Maternal behavior GO:0042711
Female behaviors associated with the care and rearing of offspring.
|
1 | P06537 (/IGI) |
Glucocorticoid receptor signaling pathway GO:0042921
Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor.
|
1 | P06537 (/IDA) |
Glucocorticoid receptor signaling pathway GO:0042921
Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor.
|
1 | P06537 (/IMP) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q62986 (/IDA) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q63449 (/IMP) |
Negative regulation of vascular permeability GO:0043116
Any process that reduces the extent to which blood vessels can be pervaded by fluid.
|
1 | P06536 (/IMP) |
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
|
1 | P19091 (/IMP) |
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
1 | Q9IAC6 (/IDA) |
Regulation of neuron apoptotic process GO:0043523
Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
|
1 | Q62986 (/IDA) |
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
|
1 | P06537 (/IGI) |
Positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568
Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling.
|
1 | P19091 (/IMP) |
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
|
1 | P07812 (/ISS) |
Cell dedifferentiation GO:0043697
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
|
1 | Q61539 (/IDA) |
Single-organism reproductive behavior GO:0044704
The specific behavior of an organism that is associated with reproduction involving a single organism.
|
1 | P15207 (/IDA) |
Response to human chorionic gonadotropin GO:0044752
Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
|
1 | Q62986 (/IEP) |
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
|
1 | Q63449 (/IEP) |
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
|
1 | Q62986 (/IMP) |
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
1 | Q62986 (/IEP) |
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
|
1 | Q61539 (/IMP) |
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
|
1 | P10275 (/IMP) |
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
|
1 | P19091 (/ISO) |
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
|
1 | Q5QJV7 (/IMP) |
Regulation of osteoclast differentiation GO:0045670
Any process that modulates the frequency, rate or extent of osteoclast differentiation.
|
1 | Q5QJV7 (/IMP) |
Negative regulation of integrin biosynthetic process GO:0045720
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
|
1 | P10275 (/IDA) |
Negative regulation of integrin biosynthetic process GO:0045720
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
|
1 | P19091 (/ISO) |
Positive regulation of integrin biosynthetic process GO:0045726
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
|
1 | P10275 (/IDA) |
Positive regulation of integrin biosynthetic process GO:0045726
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
|
1 | P19091 (/ISO) |
Positive regulation of epidermal growth factor receptor signaling pathway GO:0045742
Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
|
1 | Q62986 (/IMP) |
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q63449 (/IEP) |
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P11475 (/ISS) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P19091 (/IGI) |
Positive regulation of transcription from RNA polymerase III promoter GO:0045945
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III promoter.
|
1 | P10275 (/IDA) |
Positive regulation of transcription from RNA polymerase III promoter GO:0045945
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III promoter.
|
1 | P19091 (/ISO) |
Male sex differentiation GO:0046661
The establishment of the sex of a male organism by physical differentiation.
|
1 | P15207 (/IMP) |
Response to arsenic-containing substance GO:0046685
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
|
1 | P06536 (/IDA) |
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
1 | P16058 (/IMP) |
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | P49843 (/IDA) |
Response to mercury ion GO:0046689
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
|
1 | P06536 (/IEP) |
Chromatin-mediated maintenance of transcription GO:0048096
Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.
|
1 | P06536 (/IMP) |
Lung alveolus development GO:0048286
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
|
1 | Q00175 (/IMP) |
Negative regulation of behavior GO:0048521
Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
|
1 | Q62986 (/IDA) |
Bursa of Fabricius development GO:0048540
The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.
|
1 | Q689Y8 (/IMP) |
Reproductive structure development GO:0048608
The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.
|
1 | P19091 (/IMP) |
Regulation of developmental growth GO:0048638
Any process that modulates the frequency, rate or extent of developmental growth.
|
1 | P19091 (/IMP) |
Animal organ formation GO:0048645
The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.
|
1 | P19091 (/IMP) |
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
|
1 | Q62986 (/IMP) |
Muscle fiber development GO:0048747
The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
|
1 | H0ZRT6 (/IMP) |
Male genitalia morphogenesis GO:0048808
The process in which the anatomical structures of male genitalia are generated and organized.
|
1 | P19091 (/IMP) |
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
|
1 | Q61539 (/IMP) |
Posterior lateral line neuromast primordium migration GO:0048920
The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
|
1 | P57717 (/IGI) |
Posterior lateral line neuromast primordium migration GO:0048920
The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
|
1 | P57717 (/IMP) |
Regulation of epithelial cell proliferation GO:0050678
Any process that modulates the frequency, rate or extent of epithelial cell proliferation.
|
1 | Q00175 (/IMP) |
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
|
1 | Q62986 (/IDA) |
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | Q9YHZ7 (/IMP) |
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
|
1 | P19091 (/IMP) |
Progesterone receptor signaling pathway GO:0050847
Any series of molecular signals generated as a consequence of a progesterone binding to its receptor.
|
1 | Q00175 (/IDA) |
Positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
1 | Q92731 (/IDA) |
Positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
1 | O08537 (/ISO) |
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
1 | P10275 (/IMP) |
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
1 | P19091 (/ISO) |
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
1 | Q5QJV7 (/IMP) |
Protein oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | P10275 (/IDA) |
Protein oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | P19091 (/ISO) |
Response to corticosterone GO:0051412
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
|
1 | P06536 (/IEP) |
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | P06536 (/IEP) |
Response to electrical stimulus GO:0051602
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
|
1 | P06536 (/IEP) |
Sertoli cell development GO:0060009
The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.
|
1 | Q62986 (/IEP) |
Sertoli cell proliferation GO:0060011
The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
|
1 | Q62986 (/IMP) |
Uterus development GO:0060065
The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.
|
1 | O08537 (/IGI) |
Vagina development GO:0060068
The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.
|
1 | O08537 (/IGI) |
Smooth muscle relaxation of the bladder outlet GO:0060085
A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body.
|
1 | F1SV76 (/IMP) |
Male mating behavior GO:0060179
The specific behavior of a male organism that is associated with reproduction.
|
1 | Q689Y8 (/IMP) |
Female mating behavior GO:0060180
The specific behavior of a female organism that is associated with reproduction.
|
1 | Q63449 (/IMP) |
Positive regulation of penile erection GO:0060406
Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
|
1 | P15207 (/IMP) |
Activation of prostate induction by androgen receptor signaling pathway GO:0060520
Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.
|
1 | P19091 (/IMP) |
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
1 | Q62986 (/IMP) |
Morphogenesis of an epithelial fold GO:0060571
The morphogenetic process in which an epithelial sheet bends along a linear axis.
|
1 | P19091 (/IMP) |
Lateral sprouting involved in mammary gland duct morphogenesis GO:0060599
The process in which a branch forms along the side of a mammary duct.
|
1 | P19091 (/IMP) |
Mammary gland duct morphogenesis GO:0060603
The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.
|
1 | P06537 (/IMP) |
Regulation of prostatic bud formation GO:0060685
Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
|
1 | P19091 (/IGI) |
Prostate gland growth GO:0060736
The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.
|
1 | P15207 (/IEP) |
Prostate gland growth GO:0060736
The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.
|
1 | P19091 (/IMP) |
Epithelial cell differentiation involved in prostate gland development GO:0060742
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.
|
1 | P19091 (/IMP) |
Epithelial cell maturation involved in prostate gland development GO:0060743
The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
|
1 | O08537 (/IMP) |
Mammary gland alveolus development GO:0060749
The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.
|
1 | P19091 (/IMP) |
Negative regulation of androgen receptor signaling pathway GO:0060766
Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.
|
1 | O08537 (/IMP) |
Positive regulation of epithelial cell proliferation involved in prostate gland development GO:0060769
Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.
|
1 | P19091 (/IDA) |
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
1 | P06536 (/IMP) |
Positive regulation of cell growth involved in cardiac muscle cell development GO:0061051
Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
|
1 | P06536 (/IMP) |
Reproductive system development GO:0061458
The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.
|
1 | P19091 (/IGI) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q62986 (/IDA) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q62986 (/IMP) |
Cellular response to magnetism GO:0071259
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.
|
1 | Q62986 (/IEP) |
Cellular response to magnesium ion GO:0071286
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
|
1 | P06536 (/IEP) |
Cellular response to gonadotropin stimulus GO:0071371
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
|
1 | Q63449 (/IEP) |
Cellular response to luteinizing hormone stimulus GO:0071373
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.
|
1 | Q63449 (/IEP) |
Cellular response to steroid hormone stimulus GO:0071383
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
1 | P04150 (/IDA) |
Cellular response to steroid hormone stimulus GO:0071383
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
1 | P15207 (/IEP) |
Cellular response to steroid hormone stimulus GO:0071383
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
1 | P10275 (/IMP) |
Cellular response to estrogen stimulus GO:0071391
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
|
1 | P57717 (/IDA) |
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | Q92731 (/IDA) |
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | Q62986 (/IEP) |
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | Q9YHZ7 (/IMP) |
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | O08537 (/ISO) |
Cellular response to testosterone stimulus GO:0071394
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
1 | P19091 (/IDA) |
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | Q62986 (/IEP) |
Cellular response to dexamethasone stimulus GO:0071549
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
|
1 | P06537 (/ISO) |
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
1 | P04150 (/IDA) |
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
1 | P06537 (/ISO) |
Positive regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071931
Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
|
1 | Q61539 (/IMP) |
Seminiferous tubule development GO:0072520
The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.
|
1 | P19091 (/IGI) |
Seminiferous tubule development GO:0072520
The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.
|
1 | P19091 (/IMP) |
Regulation of establishment of protein localization to plasma membrane GO:0090003
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
|
1 | P10275 (/IDA) |
Regulation of establishment of protein localization to plasma membrane GO:0090003
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
|
1 | P19091 (/ISO) |
Positive regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090282
Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
|
1 | Q61539 (/IMP) |
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
|
1 | Q62986 (/IMP) |
Positive regulation of cellular response to insulin stimulus GO:1900078
Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.
|
1 | Q5QJV7 (/IMP) |
Negative regulation of glucocorticoid mediated signaling pathway GO:1900170
Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway.
|
1 | P06537 (/IDA) |
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
|
1 | Q62986 (/IDA) |
Response to salt GO:1902074
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
|
1 | Q62986 (/IEP) |
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
|
1 | Q61539 (/IDA) |
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
|
1 | Q61539 (/IMP) |
Response to 11-deoxycorticosterone GO:1903496
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.
|
1 | Q9IAC6 (/IDA) |
Response to bisphenol A GO:1903925
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.
|
1 | Q62986 (/IEP) |
Negative regulation of granulosa cell apoptotic process GO:1904709
Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.
|
1 | Q63449 (/IMP) |
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
|
1 | Q61539 (/IDA) |
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
|
1 | Q61539 (/IMP) |
Negative regulation of feeding behavior GO:2000252
Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.
|
1 | Q62986 (/IMP) |
Positive regulation of glucocorticoid receptor signaling pathway GO:2000324
Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway.
|
1 | P06536 (/IDA) |
Negative regulation of reactive oxygen species metabolic process GO:2000378
Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.
|
1 | Q62986 (/IMP) |
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
|
1 | Q61539 (/IMP) |
Negative regulation of extrinsic apoptotic signaling pathway GO:2001237
Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.
|
1 | P10275 (/IDA) |
Negative regulation of extrinsic apoptotic signaling pathway GO:2001237
Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.
|
1 | P19091 (/ISO) |
There are 60 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
70 |
A0A023PI52 (/ISS)
A0A087RF69 (/ISS)
A0A091F184 (/ISS)
A0A091FM40 (/ISS)
A0A091GQZ1 (/ISS)
A0A091IP29 (/ISS)
A0A091IR26 (/ISS)
A0A091K193 (/ISS)
A0A091PAL5 (/ISS)
A0A091R950 (/ISS)
(60 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
51 |
A0A023PI52 (/ISS)
A0A087RF69 (/ISS)
A0A091F184 (/ISS)
A0A091FM40 (/ISS)
A0A091GQZ1 (/ISS)
A0A091IP29 (/ISS)
A0A091IR26 (/ISS)
A0A091K193 (/ISS)
A0A091PAL5 (/ISS)
A0A091R950 (/ISS)
(41 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
32 |
A0A060X747 (/IDA)
A0A1D5PRD7 (/IDA)
F6PEW1 (/IDA)
G1K325 (/IDA)
G1NEJ8 (/IDA)
O08537 (/IDA)
O08580 (/IDA)
P04150 (/IDA)
P06536 (/IDA)
P06537 (/IDA)
(22 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
18 |
A0A1D5PRD7 (/IDA)
F6PEW1 (/IDA)
O08537 (/IDA)
P04150 (/IDA)
P06536 (/IDA)
P06537 (/IDA)
P10275 (/IDA)
P15207 (/IDA)
P19091 (/IDA)
P22199 (/IDA)
(8 more) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
12 |
O97775 (/ISS)
O97776 (/ISS)
O97952 (/ISS)
O97960 (/ISS)
P07812 (/ISS)
P15207 (/ISS)
P19091 (/ISS)
P49699 (/ISS)
Q6QT55 (/ISS)
Q8MIK0 (/ISS)
(2 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
9 | E5KQF5 (/IDA) E5KQF6 (/IDA) F1D8N4 (/IDA) G1K325 (/IDA) P04150 (/IDA) P06537 (/IDA) P07812 (/IDA) Q63449 (/IDA) Q6RKQ3 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
8 | O95718 (/TAS) P04150 (/TAS) P06401 (/TAS) P08235 (/TAS) P10275 (/TAS) P11474 (/TAS) P62508 (/TAS) Q92731 (/TAS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | F1Q8K8 (/IC) F1QH45 (/IC) F6PD98 (/IC) P16058 (/IC) Q00175 (/IC) Q6Q6F3 (/IC) Q6Q6F6 (/IC) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
7 | A0A0D9SFL9 (/IDA) B0ZBF6 (/IDA) E5KQF5 (/IDA) E5KQF6 (/IDA) F1D8N4 (/IDA) P04150 (/IDA) P08235 (/IDA) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
6 | C6KE15 (/ISS) P50242 (/ISS) Q0H3B5 (/ISS) Q4ZHP9 (/ISS) Q5I1Z4 (/ISS) Q5YFR8 (/ISS) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
4 | A0A060X747 (/IDA) P16058 (/IDA) P49843 (/IDA) Q9IAC6 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | P04150 (/TAS) P06401 (/TAS) P08235 (/TAS) P10275 (/TAS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | O08537 (/ISO) P06537 (/ISO) P19091 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P04150 (/TAS) P11474 (/TAS) Q92731 (/TAS) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | Q62986 (/IDA) Q63449 (/IDA) Q92731 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | P19091 (/IDA) Q62986 (/IDA) Q63449 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | P06537 (/IDA) Q9IAK1 (/IDA) W5UDK8 (/IDA) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
3 | P06536 (/IDA) Q62986 (/IDA) Q63449 (/IDA) |
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
|
3 | P04150 (/IDA) P06536 (/IDA) P10275 (/IDA) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | P07812 (/IDA) P10275 (/IDA) |
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
|
2 | O95718 (/ISS) P11475 (/ISS) |
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
|
2 | P11474 (/IDA) Q569H8 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P49843 (/IMP) Q6RKQ3 (/IMP) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | P06537 (/ISO) Q8VII8 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P49843 (/IMP) Q6RKQ3 (/IMP) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P06537 (/ISO) P19091 (/ISO) |
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
2 | P11474 (/IDA) Q569H8 (/IDA) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
2 | P15207 (/IDA) Q63449 (/IDA) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
2 | P15207 (/IDA) Q63449 (/IDA) |
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
2 | P07812 (/IDA) Q62986 (/IDA) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
2 | P06536 (/IDA) Q63449 (/IDA) |
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
|
2 | Q62986 (/IDA) Q63449 (/IDA) |
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
|
2 | P06537 (/ISO) P19091 (/ISO) |
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | P07812 (/IDA) P08235 (/IDA) |
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
|
2 | P11474 (/IDA) Q569H8 (/IDA) |
Basolateral part of cell GO:1990794
The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.
|
2 | P49843 (/IDA) Q9IAC6 (/IDA) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | P19091 (/ISO) |
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
|
1 | Q61539 (/IMP) |
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | P06537 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P19091 (/IPI) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P62509 (/NAS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P04150 (/TAS) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O08537 (/ISO) |
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | P04150 (/TAS) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q63449 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9IAC6 (/IMP) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P06537 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P07812 (/ISS) |
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
|
1 | Q62986 (/IDA) |
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane in asymetric synapses. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
1 | P06536 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9IAC6 (/IMP) |
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
|
1 | P07812 (/IDA) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
1 | P10275 (/IDA) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
1 | P19091 (/ISO) |
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
1 | P07812 (/ISS) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q62986 (/IDA) |
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q8VII8 (/ISO) |
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
|
1 | Q63449 (/IDA) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
1 | Q9IAC6 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q62986 (/IDA) |