CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1180 | Golgi alpha-mannosidase II |
Domain Context
CATH Clusters
| Superfamily | Golgi alpha-mannosidase II |
| Functional Family | Trehalose synthase TreS |
Enzyme Information
| 3.2.1.1 |
Alpha-amylase.
based on mapping to UniProt I6X8K8
Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.
-!- Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration. -!- The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed.
|
| 5.4.99.- |
Transferring other groups.
based on mapping to UniProt I6X8K8
|
| 5.4.99.16 |
Maltose alpha-D-glucosyltransferase.
based on mapping to UniProt I6X8K8
Maltose = alpha,alpha-trehalose.
|
UniProtKB Entries (1)
| I6X8K8 |
I6X8K8_MYCTU
Mycobacterium tuberculosis H37Rv
Trehalose synthase
|
PDB Structure
| PDB | 4LXF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Synthesis of alpha-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2.
Acs Chem.Biol.
|
