CATH Domain 3uyyA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.10	D-amino Acid Aminotransferase; Chain A, domain 2
	3.20.10.10	D-amino Acid Aminotransferase, subunit A, domain 2

Domain Context

CATH Clusters

Superfamily	D-amino Acid Aminotransferase, subunit A, domain 2
Functional Family	Branched-chain amino acid aminotransferase

Enzyme Information

2.6.1.42

Branched-chain-amino-acid transaminase.

based on mapping to UniProt Q9RTX5

(1) L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate. (2) L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate. (3) L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate.

-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

Q9RTX5

Q9RTX5_DEIRA

Deinococcus radiodurans R1

Branched-chain-amino-acid aminotransferase

PDB Structure

PDB	3UYY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structures of Complexes of the Branched-Chain Aminotransferase from Deinococcus radiodurans with alpha-Ketoisocaproate and L-Glutamate Suggest the Radiation Resistance of This Enzyme for Catalysis Chen, C.D., Lin, C.H., Chuankhayan, P., Huang, Y.C., Hsieh, Y.C., Huang, T.F., Guan, H.H., Liu, M.Y., Chang, W.C., Chen, C.J. J.Bacteriol.