CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.10 | Arc Repressor Mutant, subunit A | |
1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Functional Family | ATP-dependent DNA helicase RuvB |
Enzyme Information
3.6.4.12 |
DNA helicase.
based on mapping to UniProt Q9PMT7
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
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UniProtKB Entries (1)
Q9PMT7 |
RUVB_CAMJE
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Holliday junction ATP-dependent DNA helicase RuvB
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PDB Structure
PDB | 3PFI |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
2.7 Angstrom resolution crystal structure of a probable holliday junction DNA helicase (ruvB) from Campylobacter jejuni subsp. jejuni NCTC 11168 in complex with adenosine-5'-diphosphate
To be Published
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