CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Ras family small GTPase |
Enzyme Information
| 3.6.5.2 |
Small monomeric GTPase.
based on mapping to UniProt Q76NM4
GTP + H(2)O = GDP + phosphate.
-!- A family of about 50 enzymes with a molecular mass of 21 kDa that are distantly related to the alpha-subunit of EC 3.6.1.46. -!- Involved in cell-growth regulation (Ras subfamily), membrane vesicle traffic and uncoating (Rab and ARF subfamilies), nuclear protein import (Ran subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies). -!- Formerly EC 3.6.1.47.
|
UniProtKB Entries (1)
| Q76NM4 |
Q76NM4_PLAF7
Plasmodium falciparum 3D7
Ras-related protein Rab-11A
|
PDB Structure
| PDB | 3BFK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of Plasmodium falciparum Rab11a in complex with GDP.
To be Published
|
