CATH Domain 2i5eA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
	3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family	2-phospho-L-lactate guanylyltransferase CofC

Enzyme Information

2.7.7.68

2-phospho-L-lactate guanylyltransferase.

based on mapping to UniProt Q8PU52

(2S)-2-phospholactate + GTP = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate.

-!- This enzyme is involved in the biosynthesis of coenzyme F420, a redox-active cofactor found in all methanogenic archaea, as well as some eubacteria.

UniProtKB Entries (1)

Q8PU52

COFC_METMA

Methanosarcina mazei Go1

2-phospho-L-lactate guanylyltransferase

PDB Structure

PDB	2I5E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The crystal structure of a hypothetical protein MM_2497 from Methanosarcina mazei Go1 Tan, K., Du, J., Clancy, S., Joachimiak, A. To be Published