CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1180 | Golgi alpha-mannosidase II |
Domain Context
CATH Clusters
| Superfamily | Golgi alpha-mannosidase II |
| Functional Family | Putative glucosylceramidase 3 |
Enzyme Information
| 3.2.1.45 |
Glucosylceramidase.
based on mapping to UniProt P04062
D-glucosyl-N-acylsphingosine + H(2)O = D-glucose + N-acylsphingosine.
-!- Also acts on glucosylsphingosine (cf. EC 3.2.1.62).
|
UniProtKB Entries (1)
| P04062 |
GLCM_HUMAN
Homo sapiens
Glucosylceramidase
|
PDB Structure
| PDB | 1OGS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-Ray Structure of Human Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease
Embo Rep.
|
