CATH Domain 1j6uA03

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.190	Protein-Tyrosine Phosphatase; Chain A
	3.90.190.20	Mur ligase, C-terminal domain

Superfamily	Mur ligase, C-terminal domain
Functional Family	UDP-N-acetylmuramate--L-alanine ligase

6.3.2.8

UDP-N-acetylmuramate--L-alanine ligase.

based on mapping to UniProt Q9WY73

ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP- N-acetyl-alpha-D-muramoyl-L-alanine.

-!- Involved in the synthesis of a cell-wall peptide.

MURC_THEMA

Thermotoga maritima MSB8

UDP-N-acetylmuramate--L-alanine ligase

PDB	1J6U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution. Spraggon, G., Schwarzenbacher, R., Kreusch, A., Lee, C.C., Abdubek, P., Ambing, E., Biorac, T., Brinen, L.S., Canaves, J.M., Cambell, J., Chiu, H.J., Dai, X., Deacon, A.M., DiDonato, M., Elsliger, M.A., Eshagi, S., Floyd, R., Godzik, A., Grittini, C., Grzechnik, S.K., Hampton, E., Jaroszewski, L., Karlak, C., Klock, H.E., Koesema, E., Kovarik, J.S., Kuhn, P., Levin, I., McMullan, D., McPhillips, T.M., Miller, M.D., Morse, A., Moy, K., Ouyang, J., Page, R., Quijano, K., Robb, A., Stevens, R.C., van den Bedem, H., Velasquez, J., Vincent, J., von Delft, F., Wang, X., West, B., Wolf, G., Xu, Q., Hodgson, K.O., Wooley, J., Lesley, S.A., Wilson, I.A. Proteins