The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Medium-chain alcohol dehydrogenases, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
S-
hydroxymethyl
1463
3D
3qj5B01 - 93.6
2
602
3D
5envB01 - 95.9
3
471
3D
3gfbD01 - 70.6
4
390
3D
2cf6A01 - 93.4
5
294
3D
3qwbD01 - 95.5
6
232
3D
4rquB01 - 78.3
7
197 - - 91.9
8
194
3D
1pl8D01 - 85.7
9
146
3D
2vn8B01 - 93.0
10
144
3D
2vcyB01 - 81.1
12
120
3D
1o8cD01 - 43.3
11
117 - - 43.4
13
102
3D
3m6iB01 - 44.9
14
91 - - 88.0
15
90
3D
2vz9B07 - 74.3
19
85
3D
2y05D01 - 82.4
17
78
3D
1q1nA01 - 79.0
16
77
3D
1yb5B01 - 93.4
18
NAD
P
70 - - 88.5
20
62 - - 39.3
21
59
3D
4ueoB01 - 10.7
23
57
3D
2x7hB01 - 77.1
22
49 - - 96.3
24
45 - - 22.0
25
43
3D
1uufA01 - 34.8
49
41
3D
2j3kB01 - 83.2
26
39 - - 14.1
27
36 - - 51.4
28
36
3D
5dp2A01 - 88.2
33
35
3D
2obyE01 - 77.7
29
33 - - 65.8
32
32
3D
3slkB02 - 76.3
74
31
3D
2cdcD01 - 83.2
31
R,R
30 - - 65.3
30
30 - - 46.3
47
R
29
3D
4c4oD01 - 88.2
73
28
3D
5lbxB01 - 35.0
35
27 - - 74.8
34
27 - - 1.4
36
25 - - 26.9
39
23 - - 35.8
37
23 - - 26.1
38
23 - - 83.2
40
19 - - 87.3
41
18 - - 75.3
42
17 - - 23.8
43
14 - - 93.1
44
14 - - 17.9
46
14 - - 70.4
45
14 - - 7.7
48
13 - - 2.5
75
13
3D
2vwqA01 - 22.1
50
12 - - 37.0
55
11 - - 14.5
56
11 - - 11.0
51
Zinc
11 - - 64.4
52
11 - - 75.5
53
11 - - 16.8
54
11 - - 0.0
61
10 - - 56.5
60
10 - - 16.9
58
10 - - 14.1
57
10 - - 34.1
59
10 - - 0.0
68
9 - - 0.4
69
9 - - 100.0
63
9 - - 4.4
62
9 - - 21.1
64
9 - - 15.6
65
9 - - 10.7
66
9 - - 5.7
67
9 - - 89.4
70
8 - - 27.4
71
8 - - 88.8
72
8 - - 96.8
76
7 - - 15.1
77
7 - - 10.9
78
6 - - 67.8
80
6 - - 20.6
82
6 - - 87.0
81
6 - - 10.6
79
6 - - 14.5
89
5 - - 17.1
91
5 - - 5.7
92
5 - - 84.2
90
5 - - 0.0
84
5 - - 18.5
93
class III
5 - - 63.8
83
5 - - 67.5
85
5 - - 7.2
86
5 - - 14.2
87
5 - - 0.7
88
5 - - 0.7
99
4 - - 78.0
100
4 - - 74.5
96
4 - - 0.0
94
4 - - 63.4
95
4 - - 14.4
98
4 - - 10.4
97
4 - - 0.0
112
3 - - 61.9
105
3 - - 2.3
111
3 - - 74.2
110
Zn containing Adh-13
3 - - 0.0
102
3 - - 42.8
103
3 - - 3.6
101
class V
3 - - 64.3
108
3 - - 5.1
109
3 - - 17.4
106
3 - - 2.1
107
3 - - 9.9
104
3 - - 0.0
128
2 - - 1.6
132
2 - - 0.0
139
2 - - 40.1
129
class III
2 - - 35.5
124
2 - - 5.4
113
2 - - 0.0
131
2 - - 0.0
141
2 - - 20.3
119
2 - - 2.9
125
2 - - 0.0
118
2 - - 3.3
126
2 - - 36.9
133
2 - - 0.0
134
2 - - 42.0
127
2 - - 4.0
136
AFU_orthologue AFUA_2G04590
2 - - 0.0
116
2 - - 12.2
137
2 - - 3.2
117
2 - - 0.0
135
2 - - 40.8
120
2 - - 7.0
121
2 - - 0.0
138
2 - - 37.7
130
2 - - 0.0
140
2 - - 29.0
115
2 - - 0.0
122
2 - - 1.5
114
2 - - 0.7
123
2 - - 0.0
191
1 - - 0.0
170
1 - - 0.0
142
1 - - 0.0
184
1 - - 0.0
181
1 - - 0.0
158
1 - - 0.0
165
1 - - 0.0
149
1 - - 0.0
168
1 - - 0.0
178
1 - - 0.0
192
1 - - 0.0
199
1 - - 0.0
183
1 - - 0.0
148
1 - - 0.0
157
1 - - 0.0
179
1 - - 0.0
193
1 - - 0.0
144
1 - - 0.0
177
1 - - 0.0
163
1 - - 0.0
186
1 - - 0.0
156
1 - - 0.0
196
1 - - 0.0
194
1 - - 0.0
171
1 - - 0.0
176
1 - - 0.0
143
1 - - 0.0
166
1 - - 0.0
185
1 - - 0.0
153
1 - - 0.0
180
1 - - 0.0
187
1 - - 0.0
155
1 - - 0.0
175
1 - - 0.0
198
1 - - 0.0
202
1 - - 0.0
154
1 - - 0.0
147
1 - - 0.0
145
1 - - 0.0
152
1 - - 0.0
200
1 - - 0.0
161
1 - - 0.0
195
1 - - 0.0
174
1 - - 0.0
188
1 - - 0.0
146
1 - - 0.0
164
1 - - 0.0
160
1 - - 0.0
189
1 - - 0.0
151
1 - - 0.0
182
1 - - 0.0
167
1 - - 0.0
173
1 - - 0.0
197
1 - - 0.0
150
1 - - 0.0
159
1 - - 0.0
162
1 - - 0.0
201
1 - - 0.0
169
1 - - 0.0
190
1 - - 0.0
172
1 - - 0.0